Kipling R M, Cruickshank A N
Anaesthesia. 1985 Mar;40(3):281-4. doi: 10.1111/j.1365-2044.1985.tb10756.x.
Organophosphate insecticides are widely used agents which are quickly absorbed through the skin and mucous membranes. The effects of acute exposure to these agents can be severe and intensive therapy may be required. Specific drugs are available to reverse the muscarinic, nicotinic and central effects of these poisons. When given early they are very effective and early diagnosis and treatment may therefore be life-saving. A case of acute poisoning with an organophosphate anticholinesterase insecticide is reported. The signs and symptoms of acute poisoning are described and a rational approach to specific treatment is discussed.
有机磷酸酯类杀虫剂是广泛使用的药剂，可通过皮肤和粘膜迅速吸收。急性接触这些药剂的影响可能很严重，可能需要强化治疗。有特效药物可用于逆转这些毒物的毒蕈碱样、烟碱样和中枢效应。早期使用时，它们非常有效，因此早期诊断和治疗可能会挽救生命。本文报告一例有机磷酸酯类抗胆碱酯酶杀虫剂急性中毒病例。描述了急性中毒的体征和症状，并讨论了特效治疗的合理方法。
