Wilcox James, Lobo Daniela, Anderson Sierra
Department of Family Medicine, Indiana University School of Medicine, 980 Indiana Avenue Lockefield Village 1164, Indianapolis, IN 46202, USA.
Department of Family Medicine, Indiana University School of Medicine, 1040 Wishard Boulvard, Dunlap Building, Indianapolis, IN 46202, USA.
Prim Care. 2025 Mar;52(1):87-97. doi: 10.1016/j.pop.2024.09.010. Epub 2025 Jan 3.
This study provides a comprehensive overview of sinusitis, detailing its pathophysiology, clinical manifestations, diagnostic criteria, and management strategies. Sinusitis, characterized by inflammation of the paranasal sinuses, can be acute, subacute, recurrent, or chronic, with distinct clinical presentations and treatment approaches. Diagnosis relies on clinical evaluation, imaging studies, and occasionally nasal endoscopy. Treatment encompasses both pharmacologic and non-pharmacological interventions, including antibiotics for bacterial cases and intranasal corticosteroids to reduce inflammation. Surgical interventions like functional endoscopic sinus surgery may be required for refractory cases. Emerging therapies, such as biologics and minimally invasive procedures, offer promising alternatives to traditional management approaches.
本研究全面概述了鼻窦炎，详细阐述了其病理生理学、临床表现、诊断标准和管理策略。鼻窦炎以鼻窦炎症为特征，可分为急性、亚急性、复发性或慢性，具有不同的临床表现和治疗方法。诊断依靠临床评估、影像学检查，偶尔还需要鼻内镜检查。治疗包括药物和非药物干预，细菌性病例使用抗生素，鼻内使用皮质类固醇以减轻炎症。难治性病例可能需要功能性鼻内镜鼻窦手术等外科干预。生物制剂和微创手术等新兴疗法为传统管理方法提供了有前景的替代方案。
