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瑞士白化大鼠肾脏和肝脏暴露于家用脱毛激光辐射的组织学效应。

Histological effects of exposure to home hair removal laser radiation in kidney and liver of Swiss albino rats.

作者信息

Madlool Zaman Subhi, Akar Rasha Ali, Kudhair Fadhil Abbas

机构信息

Department of Biology, Faculty of Education for Pure Science, University of Thi-Qar, Thi-Qar, 64001, Iraq.

College of Pharmacy, University of Thi-Qar, 64001, Thi-Qar, Iraq.

出版信息

Lasers Med Sci. 2025 Feb 13;40(1):85. doi: 10.1007/s10103-025-04340-y.

DOI:10.1007/s10103-025-04340-y
PMID:39939488
Abstract

Although laser irradiation is becoming a common practice in medicine and is now considered a preferred therapy for many challenging pain management issues, there is no clear understanding of its side effects on physiological and histological parameters. The current study aimed to determine the safety of home laser irradiation on liver and kidney tissues. Male Swiss albino rats were purchased from the Department of Biology at Thi-Qar University. The rats were randomly divided into two equivalent groups, each containing six rats: a control group that was left unexposed and a second group that was exposed to six pulses of radiation per day (with a pulse duration of 2-3 milliseconds) for two weeks. The results of the current study did not show any changes in the kidney and liver tissues of the group treated with the laser. We concluded that using a home laser has no effect on kidney and liver tissues.

摘要

尽管激光照射在医学领域正变得越来越普遍,并且现在被认为是许多具有挑战性的疼痛管理问题的首选疗法,但对于其对生理和组织学参数的副作用尚无清晰的认识。当前的研究旨在确定家用激光照射对肝脏和肾脏组织的安全性。雄性瑞士白化大鼠购自济加尔大学的生物学系。大鼠被随机分为两个相等的组,每组包含六只大鼠:一个未接受照射的对照组和另一个每天接受六个脉冲辐射(脉冲持续时间为2 - 3毫秒),持续两周的组。当前研究的结果并未显示激光治疗组的肾脏和肝脏组织有任何变化。我们得出结论,使用家用激光对肾脏和肝脏组织没有影响。

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本文引用的文献

1
Using the Hair Removal Laser in the Axillary Region and its Effect on Normal Microbial Flora.脱毛激光在腋窝区域的应用及其对正常微生物菌群的影响。
J Lasers Med Sci. 2020 Summer;11(3):255-261. doi: 10.34172/jlms.2020.43. Epub 2020 Jun 21.
2
Alexandrite laser induced uveitis & pigment dispersion: A case report and review of the literature.变石激光诱发葡萄膜炎及色素播散:一例病例报告并文献复习
Am J Ophthalmol Case Rep. 2020 Mar 2;18:100632. doi: 10.1016/j.ajoc.2020.100632. eCollection 2020 Jun.
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The Diagnosis and Management of Thyroid Nodules: A Review.
甲状腺结节的诊断与处理:综述
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Low-power laser irradiation inhibits PDGF-BB-induced migration and proliferation via apoptotic cell death in vascular smooth muscle cells.低功率激光照射通过诱导血管平滑肌细胞凋亡抑制血小板衍生生长因子-BB(PDGF-BB)诱导的迁移和增殖。
Lasers Med Sci. 2017 Dec;32(9):2121-2127. doi: 10.1007/s10103-017-2338-z. Epub 2017 Oct 5.
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Effects of low intensity laser in in vitro bacterial culture and in vivo infected wounds.低强度激光对体外细菌培养及体内感染伤口的影响。
Rev Col Bras Cir. 2014 Jan-Feb;41(1):49-55. doi: 10.1590/s0100-69912014000100010.
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Porcine skin damage thresholds for 0.6 to 9.5 cm beam diameters from 1070-nm continuous-wave infrared laser radiation.猪皮对于 1070nm 连续红外激光辐射,在 0.6 到 9.5cm 光束直径下的损伤阈值。
J Biomed Opt. 2014 Mar;19(3):35007. doi: 10.1117/1.JBO.19.3.035007.
7
Infrared skin damage thresholds from 1319-nm continuous-wave laser exposures.1319nm 连续波激光辐照致红外皮肤损伤阈值。
J Biomed Opt. 2013 Dec;18(12):125002. doi: 10.1117/1.JBO.18.12.125002.
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Biphasic dose response in low level light therapy.低强度光疗法中的双相剂量反应。
Dose Response. 2009 Sep 1;7(4):358-83. doi: 10.2203/dose-response.09-027.Hamblin.
9
Thermal injury causes DNA damage and lethality in unheated surrounding cells: active thermal bystander effect.热损伤导致未受热周围细胞的 DNA 损伤和致死:主动热旁观者效应。
J Invest Dermatol. 2010 Jan;130(1):86-92. doi: 10.1038/jid.2009.205.
10
Effect of pigmentation density upon 2.0 microm laser irradiation thermal response.色素沉着密度对2.0微米激光照射热响应的影响。
Health Phys. 2007 Oct;93(4):273-8. doi: 10.1097/01.HP.0000264936.67385.04.