添加粉末强化以提高铁生物利用度的大豆粉可改善体内肠道健康和氧化平衡。
Soybean Flour Fortified with Powder to Increase Iron Bioavailability Improves Gut Health and Oxidative Balance In Vivo.
作者信息
Barnabé Michele Lílian da Fonseca, Vicente Laura Célia de Oliveira Souza, Martins Karina Vitoria Cipriana, Lacerda Gabrieli Fernandes, Rodrigues Elias, Oliveira Lívya Alves, Dias Kelly Aparecida, Pereira Stephanie Michelin Santana, José Vinicius Parzanini Brilhante de São, Dias Manoela Maciel Dos Santos, Calhelha Ricardo C, Leite Luciano Bernardes, Ribeiro Lúcia, Carvalho Izabela Maria Montezano de, Silva Bárbara Pereira da, Martino Hércia Stampini Duarte, Gonçalves Reggiani Vilela, Mattos Della Lucia Ceres
机构信息
Laboratory of Vitamin Analysis, Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa 36570-900, MG, Brazil.
Laboratory of Experimental Nutrition, Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa 36570-900, MG, Brazil.
出版信息
Nutrients. 2025 Jan 25;17(3):437. doi: 10.3390/nu17030437.
BACKGROUND
Insects like have an excellent nutritional profile, including iron. However, the bioavailability of this iron and its effects on intestinal health and oxidative balance remain unclear. To enhance acceptance, insects can be used in powder form and combined with common flours.
OBJECTIVE
This study evaluates the effects of powder, alone or with soy flour, on iron bioavailability, intestinal health, and oxidative balance in rodents.
METHODS
Using the hemoglobin depletion/repletion method, 32 male Wistar rats were divided into four groups: A (standard diet + ferrous sulfate), B (diet + + soy flour), C (diet + ), and D (diet + soy flour). Hemoglobin levels, regeneration efficiency, biological value, serum markers, intestinal health, and oxidative balance were assessed.
RESULTS
Food intake, weight gain, and bioavailability measures showed no differences. However, the Gryllus + soy group showed higher weekly and final hemoglobin levels than Gryllus alone. This combination also improved acetic acid levels, fecal moisture, and oxidative balance, increasing superoxide dismutase activity while reducing peroxidation products compared to Gryllus alone.
CONCLUSION
These findings highlight the potential benefits of combining with soy flour for iron bioavailability and overall health.
背景
像蟋蟀这样的昆虫具有优异的营养成分，包括铁。然而，这种铁的生物利用度及其对肠道健康和氧化平衡的影响仍不清楚。为了提高接受度，昆虫可以制成粉末形式并与普通面粉混合使用。
目的
本研究评估蟋蟀粉单独或与大豆粉一起对啮齿动物铁生物利用度、肠道健康和氧化平衡的影响。
方法
采用血红蛋白耗竭/补充法，将32只雄性Wistar大鼠分为四组：A组（标准饮食+硫酸亚铁）、B组（饮食+蟋蟀粉+大豆粉）、C组（饮食+蟋蟀粉）和D组（饮食+大豆粉）。评估血红蛋白水平、再生效率、生物价值、血清标志物、肠道健康和氧化平衡。
结果
食物摄入量、体重增加和生物利用度指标无差异。然而，蟋蟀+大豆组的每周和最终血红蛋白水平高于单独使用蟋蟀组。与单独使用蟋蟀相比，这种组合还改善了乙酸水平、粪便湿度和氧化平衡，增加了超氧化物歧化酶活性，同时减少了过氧化产物。
结论
这些发现突出了将蟋蟀与大豆粉结合对铁生物利用度和整体健康的潜在益处。
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