Silva Laila Y S, Cavalcante Débora N, Oliveira Edinilze S C, Salvador Andreia M, Pereira Zilanir C, Consentini Julia C C, Furlaneto Gabriela, Campelo Pedro H, Sanches Edgar A, Azevedo Luciana, Bezerra Jaqueline de A
Amazon Science and Technology Studies Center, Federal Institute of Education, Science and Technology of Amazonas, Manaus 69020-120, Brazil.
In Vitro and In Vivo Nutritional and Toxicological Analysis Laboratory, Federal University of Alfenas, Alfenas 37130-000, Brazil.
Plants (Basel). 2025 Jan 26;14(3):377. doi: 10.3390/plants14030377.
Edible flowers have gained attention as unconventional food sources due to their nutritional and functional properties. This study provides novel information on the chemical composition, cytotoxicity and antiproliferative effects of flowers. The objective of this paper was to identify bioactive compounds in its flowers using one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy and liquid chromatography coupled with high-resolution mass spectrometry (LC-HRMS). The phenolic fraction of the flowers revealed bioactive compounds such as hyperoside, guaijaverin, astragalin, juglalin, and kaempferol. The results confirmed the potential of flowers as a source of phenolic compounds, emphasizing their feasibility for possible applications in the development of functional foods. Moreover, the antiproliferative assay demonstrated that the phenolic fraction inhibits cell proliferation (GI) while presenting low cytotoxicity in both cancer and normal cells.
可食用花卉因其营养和功能特性作为非传统食物来源受到了关注。本研究提供了关于花卉的化学成分、细胞毒性和抗增殖作用的新信息。本文的目的是使用一维和二维核磁共振（NMR）光谱以及液相色谱与高分辨率质谱联用（LC-HRMS）来鉴定其花朵中的生物活性化合物。花朵的酚类部分显示出生物活性化合物，如金丝桃苷、桧黄素、黄芪苷、胡桃苷和山柰酚。结果证实了花卉作为酚类化合物来源的潜力，强调了它们在功能性食品开发中可能应用的可行性。此外，抗增殖试验表明，酚类部分在抑制细胞增殖（GI）的同时，对癌细胞和正常细胞均表现出低细胞毒性。
