Korovina A M
Arkh Anat Gistol Embriol. 1985 Feb;88(2):51-6.
Swiching off the external and internal secretion of the pancreas by means of extirpation of the organ demonstrates a progressive hypoplasia of the immunocompetent tissue in the inguinal lymphatic nodes. The involution is determined by decreasing number of small, middle and large lymphocytes in the cortical part of the node. Together with the decreasing number of the lymphatic nodules, by the 20th-60th days after the operation the germinative centers become poor in middle, large lymphocytes and in lymphoblasts. Among the cells mentioned, mitotic activity is decreased. Hence, thymus-dependent, but to a greater extent, thymus--independent zones of the lymphatic nodes are subjected to involution.
通过切除胰腺来阻断其外分泌和内分泌功能,结果显示腹股沟淋巴结中免疫活性组织出现进行性发育不全。这种退化表现为淋巴结皮质中小淋巴细胞、中淋巴细胞和大淋巴细胞数量的减少。随着淋巴小结数量的减少,在术后第20至60天,生发中心的中淋巴细胞、大淋巴细胞和淋巴母细胞数量减少。在上述细胞中,有丝分裂活性降低。因此,淋巴结中依赖胸腺的区域,以及在更大程度上不依赖胸腺的区域都发生了退化。