Austin Anna E, O'Callaghan Kevin, Rushmore Julie, Cramer Ryan, McDonald Robert, Learner Emily R
At the time of the study, Anna E. Austin was with the University of North Carolina at Chapel Hill and the National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA. Kevin O'Callaghan, Julie Rushmore, Ryan Cramer, Robert McDonald, and Emily R. Learner were with the Division of STD Prevention, Centers for Disease Control and Prevention. The findings and conclusions of this study are those of the authors and do not represent the official position of the Centers for Disease Control and Prevention.
Am J Public Health. 2025 Apr;115(4):566-574. doi: 10.2105/AJPH.2024.307951. Epub 2025 Feb 13.
To estimate the association of state policies that define prenatal substance use as child abuse and mandate that health care professionals report prenatal substance use to child protective services with congenital syphilis case rates. We used 2018 to 2022 US data on congenital syphilis case notifications to the National Notifiable Diseases Surveillance System. We conducted linear regression with a generalized estimating equation approach to compare congenital syphilis case rates in states with a child abuse policy only, a mandated reporting policy only, and both polices to rates in states with neither policy. After adjustment for confounders, the rate of congenital syphilis cases was, on average, 23.5 (95% confidence interval = 2.2, 44.8) cases per 100 000 live births higher in states with both a child abuse policy and a mandated reporting policy for prenatal substance use than in states with neither policy. Rates were similar in states with a child abuse policy only and a mandated reporting policy only compared to states with neither policy. The combination of state child abuse policies and mandated reporting policies for prenatal substance use potentially contributes to higher congenital syphilis case rates. (. 2025;115(4):566-574. https://doi.org/10.2105/AJPH.2024.307951).
为了评估将产前物质使用定义为虐待儿童的州政策以及要求医疗保健专业人员向儿童保护服务机构报告产前物质使用情况与先天性梅毒病例率之间的关联。我们使用了2018年至2022年美国向国家法定传染病监测系统报告的先天性梅毒病例数据。我们采用广义估计方程方法进行线性回归，以比较仅实施虐待儿童政策的州、仅实施强制报告政策的州以及同时实施这两种政策的州与既无这两种政策的州的先天性梅毒病例率。在对混杂因素进行调整后，与既无政策的州相比，同时实施产前物质使用虐待儿童政策和强制报告政策的州，先天性梅毒病例率平均每10万例活产高出23.5例（95%置信区间 = 2.2, 44.8）。与既无政策的州相比，仅实施虐待儿童政策的州和仅实施强制报告政策的州的病例率相似。州虐待儿童政策和产前物质使用强制报告政策的结合可能导致先天性梅毒病例率升高。（. 2025;115(4):566 - 574. https://doi.org/10.2105/AJPH.2024.307951）
