Jenkinson E J, Searle R F
J Reprod Immunol. 1979 Jan-Feb;1(1):3-10. doi: 10.1016/0165-0378(79)90024-x.
The expression of I region controlled antigens on the mouse embryo and placenta has been investigated using immuno-peroxidase labelling and a mixed haemadsorption assay. The results indicate that Ia antigens are absent from selected pre- and post-implantation embryonic and trophoblastic tissues and from the trophoblast of the definitive placenta. In contrast, cells derived from the peri-placental maternal decidual tissues are Ia antigen-positive. The findings are discussed in relation to the allograft status of the conceptus and the identity and functional significance of the Ia-bearing maternal cells at the foeto-maternal interface.
利用免疫过氧化物酶标记和混合血细胞吸附试验，对小鼠胚胎和胎盘上I区控制抗原的表达进行了研究。结果表明，在选定的植入前和植入后胚胎及滋养层组织以及成熟胎盘的滋养层中不存在Ia抗原。相反，源自胎盘周围母体蜕膜组织的细胞Ia抗原呈阳性。结合孕体的同种异体移植状态以及胎儿-母体界面处携带Ia抗原的母体细胞的特性和功能意义对这些发现进行了讨论。
