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脑脊液诊断管理干预对检查数量、住院时间、抗生素处方及费用的影响。

Impact of a cerebrospinal fluid diagnostic stewardship intervention on quantity of tests, length of stay, antibiotic prescriptions, and cost.

作者信息

Pathak Aaron, Shay Sabra, Lasco Todd, Al Mohajer Mayar

机构信息

School of Medicine, Baylor College of Medicine, Houston, TX, USA.

Department of Clinical Intelligence, Premier Inc., Charlotte, NC, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2025 Feb 11;5(1):e35. doi: 10.1017/ash.2025.17. eCollection 2025.

DOI:10.1017/ash.2025.17
PMID:39950009
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11822616/
Abstract

Redundant and low-value cerebrospinal fluid analysis for suspected meningitis can increase costs and antimicrobial use. Our diagnostic stewardship intervention limited available infectious disease cerebrospinal fluid assays to seven common tests, including a multiplex polymerase chain reaction panel. There was no significant difference in the cost of testing or clinical outcomes.

摘要

对疑似脑膜炎进行多余且低价值的脑脊液分析会增加成本和抗菌药物的使用。我们的诊断管理干预措施将可用的感染性疾病脑脊液检测项目限制为七项常见检测，包括一个多重聚合酶链反应检测板。检测成本或临床结果没有显著差异。

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本文引用的文献

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Antimicrob Steward Healthc Epidemiol. 2024 Jul 26;4(1):e104. doi: 10.1017/ash.2024.343. eCollection 2024.
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Progress and Challenges in Bacterial Meningitis: A Review.细菌性脑膜炎的进展与挑战：综述
JAMA. 2022 Dec 6;328(21):2147-2154. doi: 10.1001/jama.2022.20521.
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Assessment of the Impact of a Meningitis/Encephalitis Panel on Hospital Length of Stay: A Systematic Review and Meta-Analysis.脑膜炎/脑炎检测组合对住院时间影响的评估：一项系统评价与荟萃分析
Antibiotics (Basel). 2022 Jul 30;11(8):1028. doi: 10.3390/antibiotics11081028.
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Multiplex Polymerase Chain Reaction Testing to Diagnose Central Nervous System Infections-A Doubled-Edged Sword.多重聚合酶链反应检测诊断中枢神经系统感染——一把双刃剑
J Pediatric Infect Dis Soc. 2022 Apr 30;11(4):124-125. doi: 10.1093/jpids/piab131.
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