新冠疫情改变了癌症筛查部位的流行病学情况：乳腺癌、宫颈癌、结肠癌和直肠癌。

COVID-19 pandemic shifted epidemiology for cancer screening sites: breast, cervix, colon, and rectum.

作者信息

Ishkinin Yevgeniy, Kaidarova Dilyara, Nazarbek Serzhan, Zhylkaidarova Alma, Ossikbayeva Saniya, Mussina Kamilla, Omarbayeva Nazgul

机构信息

Department of Radiation Therapy, Almaty Oncology Center, Almaty, Kazakhstan.

Kazakh Institute of Oncology and Radiology, Almaty, Kazakhstan.

出版信息

Front Oncol. 2025 Jan 30;14:1481242. doi: 10.3389/fonc.2024.1481242. eCollection 2024.

DOI:10.3389/fonc.2024.1481242

PMID:39950102

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11822355/

Abstract

BACKGROUND

This study aimed to assess the epidemiological changes in breast, cervical, colon, and rectal cancers in Kazakhstan before and during COVID-19, including early-onset cancer (EOC) diagnosed between the ages of 20 and 49, using data from the oncological service of the Republic of Kazakhstan for the 2017-2022 period.

METHODS

The cohort comprised patients aged 20 to 49 years (EOC) and 50 years and older [late-onset cancer (LOC)] from the total number of patients diagnosed each year during the study period of 2017 to 2022 for breast, cervical, colon, or rectal cancer. In order to indicate a difference in one-time intervals and characterize the global trend over the entire study period, annual percentage change (APC) and average APC (AAPC) were calculated, respectively.

RESULTS

Breast cancer detection rates increased by 22.8% for EOC and 15.9% for LOC from 2017 to 2022, and AAPC increased by 4.3% for EOC and 3.6% for LOC. During the COVID-19 restriction period, breast cancer detection rates decreased by 6.1% for EOC and 15.6% for LOC. Cervical cancer detection rates increased by 2.3% for EOC and 7.5% for LOC from 2017 to 2022, and AAPC increased by 0.9% for EOC and 1.6% for LOC. During the COVID-19 restriction period, cervical cancer detection rates decreased by 11.3% for EOC and 3.1% for LOC. Colon cancer detection rates increased by 18.4% for EOC and 14.3% for LOC from 2017 to 2022, and AAPC increased by 3.7% for EOC and 2.9% for LOC. During the COVID-19 restriction period, colon cancer detection rates decreased by 14.4% for EOC and 5.8% for LOC. Rectal cancer detection rates increased by 13.6% for EOC and 19.2% for LOC from 2017 to 2022, and AAPC increased by 3.0% for EOC and by 3.9% for LOC. During the COVID-19 restriction period, rectal cancer detection rates increased by 18.6% for EOC and decreased by 12.0% for LOC.

CONCLUSION

The epidemiological indicators of population cancer screening worsened during the COVID pandemic; the detection rate decreased by 6.1% for breast EOC and 11.3% for cervical EOC, while there was an increase by 38.0% in EOC for colon cancer in men and by 8.0% in EOC for rectal cancer in men and 31.1% in women.

摘要

背景

本研究旨在利用哈萨克斯坦共和国肿瘤服务机构2017 - 2022年期间的数据，评估新冠疫情之前及期间哈萨克斯坦乳腺癌、宫颈癌、结肠癌和直肠癌的流行病学变化，包括20至49岁诊断出的早发性癌症（EOC）。

方法

该队列包括2017年至2022年研究期间每年诊断出的乳腺癌、宫颈癌、结肠癌或直肠癌患者总数中年龄在20至49岁（早发性癌症）和50岁及以上（晚发性癌症）的患者。为了表明一次性间隔的差异并描述整个研究期间的总体趋势，分别计算了年度百分比变化（APC）和平均APC（AAPC）。

结果

2017年至2022年，早发性乳腺癌的检出率上升了22.8%，晚发性乳腺癌上升了15.9%，早发性乳腺癌的AAPC上升了4.3%，晚发性乳腺癌上升了3.6%。在新冠疫情限制期间，早发性乳腺癌的检出率下降了6.1%，晚发性乳腺癌下降了15.6%。2017年至2022年，早发性宫颈癌的检出率上升了2.3%，晚发性宫颈癌上升了7.5%，早发性宫颈癌的AAPC上升了0.9%，晚发性宫颈癌上升了1.6%。在新冠疫情限制期间，早发性宫颈癌的检出率下降了11.3%，晚发性宫颈癌下降了3.1%。2017年至2022年，早发性结肠癌的检出率上升了18.4%，晚发性结肠癌上升了14.3%，早发性结肠癌的AAPC上升了3.7%，晚发性结肠癌上升了2.9%。在新冠疫情限制期间，早发性结肠癌的检出率下降了14.4%，晚发性结肠癌下降了5.8%。2017年至2022年，早发性直肠癌的检出率上升了13.