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化脓性汗腺炎患者饮食行为的评估:一项病例对照研究。

Evaluation of eating behaviors in patients with hidradenitis suppurativa: A case-control study.

作者信息

Kaya Merve, Celik Burak, Çapar Dünya Gözde, Kahve Aybeniz Civan, Demirseren Düriye Deniz

机构信息

Department of Dermatology, Ankara City Hospital, Universiteler Mah, Ankara, 06800, Turkey.

Department of Dermatology Dinek Mah, Kulu State Hospital, Konya, 42775, Turkey.

出版信息

Arch Dermatol Res. 2025 Feb 14;317(1):408. doi: 10.1007/s00403-025-03919-3.

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory debilitating disorder that can result in significant morbidity. In addition to medical and surgical treatments, lifestyle modifications such as smoking cessation and weight control have an important benefit in HS management. These modifications can be challenging for both the patient and the clinician. The differences in eating behavior of HS patients compared to the general population are mostly unknown. Defining these differences in HS patients may help to develop more effective weight loss strategies. In our study, we aim to describe differences in eating behavior in HS patients compared to the normal population. 140 patients with HS and 140 age, gender and body mass index-matched healthy controls were included in the study. For each HS patient, Hurley and the investigator's global assessment scores were defined by a dermatologist. For each participant, Hamilton depression scale (HAM-D), Hamilton anxiety scale (HAM-A), and Dutch eating behavior questionnaire (DEBQ) were assessed by a psychiatrist. HAM-D scores were found to be significantly higher in HS group (p < 0.001), whereas HAM-A scores did not show a significant difference between HS and control group (p = 0.744). Emotional eating scores were significantly higher in HS patients compared to the control group (patients: 3.14 ± 0.96, controls: 2.29 ± 0.96, p < 0.001). Similarly, external eating scores were markedly elevated in HS patients compared to controls (patients: 3.38 ± 0.66, controls: 2.82 ± 0.73, p < 0.001). However, in terms of restrictive eating, there was no significant difference between the two groups (p = 0.783). In regression analysis, depression and anxiety scores were found not to have a significant effect on restrictive, emotional and external eating scores. Furthermore, in HS patients, a moderate positive correlation was found between emotional eating and external eating (p < 0.001). In conclusion, HS patients have tendency for emotional and external eating behavior independent from depression and anxiety.

摘要

化脓性汗腺炎(HS)是一种慢性炎症性衰弱性疾病,可导致严重的发病率。除了药物和手术治疗外,诸如戒烟和体重控制等生活方式的改变在HS的管理中具有重要益处。这些改变对患者和临床医生来说都可能具有挑战性。与普通人群相比,HS患者的饮食行为差异大多未知。明确HS患者的这些差异可能有助于制定更有效的减肥策略。在我们的研究中,我们旨在描述HS患者与正常人群在饮食行为上的差异。该研究纳入了140例HS患者以及140名年龄、性别和体重指数相匹配的健康对照者。对于每位HS患者,由一名皮肤科医生确定Hurley和研究者的整体评估分数。对于每位参与者,由一名精神科医生评估汉密尔顿抑郁量表(HAM-D)、汉密尔顿焦虑量表(HAM-A)和荷兰饮食行为问卷(DEBQ)。发现HS组的HAM-D分数显著更高(p < 0.001),而HS组和对照组之间的HAM-A分数没有显著差异(p = 0.744)。与对照组相比,HS患者的情绪化进食分数显著更高(患者:3.14 ± 0.96,对照组:2.29 ± 0.96,p < 0.001)。同样,与对照组相比,HS患者的外部进食分数明显升高(患者:3.38 ± 0.66,对照组:2.82 ± 0.73,p < 0.001)。然而,在节制性进食方面,两组之间没有显著差异(p = 0.783)。在回归分析中,发现抑郁和焦虑分数对节制性、情绪化和外部进食分数没有显著影响。此外,在HS患者中,发现情绪化进食和外部进食之间存在中度正相关(p < 0.001)。总之,HS患者存在独立于抑郁和焦虑的情绪化和外部进食行为倾向。

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