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老年女性利尿剂诱发的痛风

Diuretic-induced gout in elderly women.

作者信息

Macfarlane D G, Dieppe P A

出版信息

Br J Rheumatol. 1985 May;24(2):155-7. doi: 10.1093/rheumatology/24.2.155.

DOI:10.1093/rheumatology/24.2.155
PMID:3995213
Abstract

During a 21/2-year period, gout was diagnosed in 51 men and 9 women at the Rheumatology Unit in Bristol. The men had a mean age of 52 years and mean age of onset of gout of 46 years, whereas the women had a mean age of 82 years and a mean age of onset of 77 years. All the women were on long-term diuretic therapy compared to 33% of the men; 77% had mild impairment of renal function and 44% had tophi. The men could recall four times as many attacks of acute gout as the women. Elderly women are particularly prone to diuretic-induced tophaceous gout but less likely to present with acute gout than men.

摘要

在2年半的时间里,布里斯托尔风湿病科诊断出51名男性和9名女性患有痛风。男性的平均年龄为52岁,痛风发病的平均年龄为46岁,而女性的平均年龄为82岁,发病平均年龄为77岁。所有女性都在接受长期利尿剂治疗,相比之下,男性为33%;77%的女性有轻度肾功能损害,44%有痛风石。男性回忆起的急性痛风发作次数是女性的四倍。老年女性特别容易患利尿剂诱发的痛风石性痛风,但比男性患急性痛风的可能性小。

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1
Diuretic-induced gout in elderly women.老年女性利尿剂诱发的痛风
Br J Rheumatol. 1985 May;24(2):155-7. doi: 10.1093/rheumatology/24.2.155.
2
Diuretic induced gout: a multifactorial condition.利尿剂诱发的痛风:一种多因素疾病。
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[Gout and diuretics; still an issue].[痛风与利尿剂;仍是一个问题]
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