Macfarlane D G, Dieppe P A
Br J Rheumatol. 1985 May;24(2):155-7. doi: 10.1093/rheumatology/24.2.155.
During a 21/2-year period, gout was diagnosed in 51 men and 9 women at the Rheumatology Unit in Bristol. The men had a mean age of 52 years and mean age of onset of gout of 46 years, whereas the women had a mean age of 82 years and a mean age of onset of 77 years. All the women were on long-term diuretic therapy compared to 33% of the men; 77% had mild impairment of renal function and 44% had tophi. The men could recall four times as many attacks of acute gout as the women. Elderly women are particularly prone to diuretic-induced tophaceous gout but less likely to present with acute gout than men.
在2年半的时间里,布里斯托尔风湿病科诊断出51名男性和9名女性患有痛风。男性的平均年龄为52岁,痛风发病的平均年龄为46岁,而女性的平均年龄为82岁,发病平均年龄为77岁。所有女性都在接受长期利尿剂治疗,相比之下,男性为33%;77%的女性有轻度肾功能损害,44%有痛风石。男性回忆起的急性痛风发作次数是女性的四倍。老年女性特别容易患利尿剂诱发的痛风石性痛风,但比男性患急性痛风的可能性小。