Kartje-Tillotson G, Neafsey E J, Castro A J
Brain Res. 1985 Apr 15;332(1):103-11. doi: 10.1016/0006-8993(85)90393-2.
Intracortical microstimulation of the motor cortex in normal adult rats evoked low threshold contralateral forelimb movements and high threshold ipsilateral movements. Ablation of the opposite sensorimotor cortex in adult animals did not alter these thresholds. However, stimulation of the unablated hemisphere in adult rats that sustained unilateral sensorimotor cortical lesions as neonates elicited low threshold ipsilateral forelimb movements that were similar to contralateral movements. These low threshold ipsilateral movements may be mediated via aberrant corticofugal pathways which are known to develop following neonatal cortical lesions.
在正常成年大鼠中，对运动皮层进行皮质内微刺激可诱发低阈值的对侧前肢运动和高阈值的同侧运动。成年动物对侧感觉运动皮层的切除并未改变这些阈值。然而，在新生期遭受单侧感觉运动皮层损伤的成年大鼠中，对未受损半球的刺激会引发低阈值的同侧前肢运动，这些运动与对侧运动相似。这些低阈值的同侧运动可能是通过已知在新生期皮层损伤后发育的异常皮质离心通路介导的。
