Cohen J L
Brain Res. 1985 Apr 15;332(1):169-73. doi: 10.1016/0006-8993(85)90402-0.
Application of glycine and GABA caused inhibition of light-evoked activity from different populations of 'ON' center ganglion cells in the retina of the skate (Raja erinacea). Cells affected by glycine were not affected by GABA and vice-versa. Addition of 100 microM strychnine to the glycine-containing perfusate caused a resumption in light-evoked responses of the cells. The action of GABA was antagonized by 100 microM bicuculline methochloride, but not by picrotoxin. Autoradiography revealed the presence of [3H]glycine accumulating amacrine cells.
在鳐鱼(Raja erinacea)视网膜中,甘氨酸和γ-氨基丁酸(GABA)的应用会抑制来自不同群体的“开”中心神经节细胞的光诱发活动。受甘氨酸影响的细胞不受GABA影响,反之亦然。向含甘氨酸的灌注液中添加100微摩尔士的宁会导致细胞光诱发反应恢复。GABA的作用被100微摩尔甲基荷包牡丹碱拮抗,但不受印防己毒素拮抗。放射自显影显示存在积累[3H]甘氨酸的无长突细胞。