Katayama Y, Tsukiyama T, Tsubokawa T
Brain Res Bull. 1985 Mar;14(3):223-6. doi: 10.1016/0361-9230(85)90086-3.
Electrical potentials within the thalamus associated with the endogenous late positive component (LPC or P300) of cerebral evoked potentials were investigated in humans and cats. Essentially identical discrimination tasks using classical aversive conditioning were employed for recording LPC in both species. In humans, a negative wave within the same latency range as that of LPC was noted, with dependency on stimulus-relevance, at all thalamic and mesencephalic recording sites which included the nucl. centrum medianum, nucl. parafascicularis, and periaqueductal gray. Similar negative waves were also observed over wide areas of the thalamus of cats including specific as well as non-specific thalamic nuclei. The negative waves seen in the thalamus were generally higher in amplitude than those seen in the white matter and became unclear when the electrodes penetrated the ventral border of the thalamus.
我们对人类和猫的丘脑内与脑诱发电位的内源性晚期正成分（LPC或P300）相关的电位进行了研究。在这两个物种中，我们采用了基本相同的使用经典厌恶条件反射的辨别任务来记录LPC。在人类中，在所有包括中央中核、束旁核和导水管周围灰质在内的丘脑和中脑记录部位，都记录到了一个与LPC潜伏期范围相同的负波，该负波依赖于刺激相关性。在猫的丘脑广泛区域，包括特异性和非特异性丘脑核团，也观察到了类似的负波。丘脑中看到的负波振幅通常比白质中看到的负波更高，并且当电极穿透丘脑腹侧边界时，负波变得不清晰。
