一种97千道尔顿糖蛋白与人类卵巢癌的关联。

Association of a 97 kilodalton glycoprotein with human ovarian carcinoma.

作者信息

Rao G S, Hanjani P

出版信息

Cancer Lett. 1985 Apr;26(3):327-34. doi: 10.1016/0304-3835(85)90057-6.

Abstract

The association of a 97 kilodalton glycoprotein (97k-GP) with human ovarian epithelial tumors is reported. The 97k-GP has been found to be present in elevated levels in all the 8 serous cystadenocarcinoma specimens tested. This glycoprotein is present in small amounts in endometrial tumors and either absent or present in trace amounts in control ovaries. Subcellular localization of this glycoprotein indicates that it is a component of plasma membrane.

摘要

据报道，一种97千道尔顿糖蛋白（97k-GP）与人类卵巢上皮肿瘤有关。已发现97k-GP在所检测的所有8个浆液性囊腺癌标本中的水平升高。这种糖蛋白在子宫内膜肿瘤中含量较少，在对照卵巢中要么不存在，要么仅微量存在。这种糖蛋白的亚细胞定位表明它是质膜的一个组成部分。