Lahti A, Maibach H I
Contact Dermatitis. 1985 Mar;12(3):139-40. doi: 10.1111/j.1600-0536.1985.tb01082.x.
The contact urticariagenic properties of diethyl fumarate were studied using the guinea pig ear swelling assay and by open application on the human upper back skin. Diethyl fumarate caused non-immunologic contact urticaria in both human and guinea pig skin, and the reactions exhibited similar dose dependency and timing of maximal response.
采用豚鼠耳部肿胀试验并通过在人体上背部皮肤进行开放性敷用，对富马酸二乙酯的接触性荨麻疹原特性进行了研究。富马酸二乙酯在人和豚鼠皮肤中均引起非免疫性接触性荨麻疹，且反应表现出相似的剂量依赖性和最大反应时间。
