Jack E M, Harrison C J, Allen T D, Harris R
Chromosoma. 1985;91(5):363-8. doi: 10.1007/BF00291009.
The same C-banded human polymorphic chromosomes were observed in the light microscope (LM) and then in the scanning electron microscope (SEM) to investigate the structural changes produced by the C-banding technique. C-banded regions, which stained positively in LM, were highly condensed with tightly packed chromatin fibres, resembling non-banded chromosomes. In striking contrast, adjacent non-C-banded regions were represented by loosely arranged fibres, resembling G-banded chromosomes. The significance of these observations in relation to current theories on the effects of C-banding on chromosome structure is discussed.
在光学显微镜（LM）下观察相同的C带人类多态性染色体，然后在扫描电子显微镜（SEM）下观察，以研究C带技术产生的结构变化。在LM中呈阳性染色的C带区域高度浓缩，染色质纤维紧密堆积，类似于未带C带的染色体。形成鲜明对比的是，相邻的非C带区域由排列松散的纤维表示，类似于G带染色体。讨论了这些观察结果与当前关于C带对染色体结构影响的理论的相关性。
