Tsvetkova T G, Iankova M F
Genetika. 1979;15(10):1870-9.
C-stained polymorphic variants of chromosomes 1, 9, 13--16, 21, 22 and Y were studied in married couples with reproductive failure (200 individuals) and in control couples having normal children and no spontaneous abortions and stillbirths. Location of heterochromatic segments, their size and heteromorphism of homologues were estimated. The individuals with reproductive failure were carriers of variants of chromosomes 9 and acrocentrics with higher content of heterochromatic material as well as with heterochromatic chromosome 9 significantly more frequently as compared with control individuals.
对1、9、13 - 16、21、22号染色体以及Y染色体的C带多态性变异在有生殖功能障碍的已婚夫妇（200人）中进行了研究，并与生育正常子女且无自然流产和死产情况的对照夫妇进行了对比。对异染色质区段的位置、大小以及同源染色体的异态性进行了评估。与对照个体相比，有生殖功能障碍的个体更频繁地携带9号染色体和近端着丝粒染色体变异，这些变异具有更高含量的异染色质物质，以及明显更多的异染色质9号染色体。
