Benady Amit, Yehiel Noy, Efrima Ben, Abdellatif Adnan, Vidra Matias, Khashan Morsi, Ben-Tov Tomer, Khoury Amal
Department of Orthopedics, Tel Aviv Sourasky Medical Center, Affiliated to the Faculty of Medicine at Tel Aviv University, Tel Aviv, Israel.
Levin Center for Surgical Innovation and 3D Printing, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Sci Rep. 2025 Feb 17;15(1):5691. doi: 10.1038/s41598-025-89974-2.
Intracapsular hip fractures in patients under 65 years of age pose unique challenges, requiring optimal treatment strategies to preserve joint anatomy. This study primarily aimed to identify comorbid risk factors contributing to conversion surgery to total hip replacement (THR) due to avascular necrosis (AVN). This single-center, retrospective study included 160 patients (mean age = 50 ± 12 years, 78 males), followed up for an average of 10 years (range: 1-14 years). Fracture classifications were Garden 1 (N = 67), Garden 2 (N = 33), Garden 3 (N = 42), and Garden 4 (N = 19). Surgical procedures included Cannulated Hip Screws (CHS, N = 75), Femoral Neck System (FNS, N = 69), and Dynamic Hip Screw (DHS, N = 17). THR was required for 14 patients (8.7%) due to AVN. The mean age at conversion was 52.76 ± 15 years, with an average time to conversion of 22.2 months (range: 2-132 months). Univariate analysis identified fracture displacement (Garden 3-4), gender, smoking status, and diabetes mellitus as significant predictors for conversion surgery. Surgical method showed a trend toward significance (p = 0.08). A multivariate binary logistic regression model, including fracture displacement, gender, and smoking status as predictors, explained 45% of the variance in conversion to THR (p < 0.01). This study underscores the importance of assessing comorbid risk factors in younger patients with intracapsular femoral neck fractures. Identifying and addressing these factors may enhance the overall management of femoral neck fractures in this population.
65岁以下患者的囊内髋部骨折带来了独特的挑战,需要优化治疗策略以保留关节解剖结构。本研究主要旨在确定因缺血性坏死(AVN)导致全髋关节置换术(THR)转换手术的合并危险因素。这项单中心回顾性研究纳入了160例患者(平均年龄=50±12岁,78例男性),平均随访10年(范围:1 - 14年)。骨折分类为Garden 1型(N = 67)、Garden 2型(N = 33)、Garden 3型(N = 42)和Garden 4型(N = 19)。手术方式包括空心钉内固定(CHS,N = 75)、股骨颈系统(FNS,N = 69)和动力髋螺钉(DHS,N = 17)。14例患者(8.7%)因AVN需要进行THR。转换时的平均年龄为52.76±15岁,平均转换时间为22.2个月(范围:2 - 132个月)。单因素分析确定骨折移位(Garden 3 - 4型)、性别、吸烟状况和糖尿病是转换手术的显著预测因素。手术方式显示出显著趋势(p = 0.08)。一个多因素二元逻辑回归模型,包括骨折移位、性别和吸烟状况作为预测因素,解释了转换为THR的45%的方差(p < 0.01)。本研究强调了评估年轻囊内股骨颈骨折患者合并危险因素的重要性。识别并处理这些因素可能会改善该人群股骨颈骨折的整体管理。