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65岁以下患者囊内髋部骨折复位内固定术后10年随访期间股骨头缺血性坏死的风险评估

Risk assessment of femoral head AVN following reduction and fixation of intracapsular hip fractures in patients younger than 65 years over a 10 year follow up.

作者信息

Benady Amit, Yehiel Noy, Efrima Ben, Abdellatif Adnan, Vidra Matias, Khashan Morsi, Ben-Tov Tomer, Khoury Amal

机构信息

Department of Orthopedics, Tel Aviv Sourasky Medical Center, Affiliated to the Faculty of Medicine at Tel Aviv University, Tel Aviv, Israel.

Levin Center for Surgical Innovation and 3D Printing, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

出版信息

Sci Rep. 2025 Feb 17;15(1):5691. doi: 10.1038/s41598-025-89974-2.

DOI:10.1038/s41598-025-89974-2
PMID:39962325
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11832920/
Abstract

Intracapsular hip fractures in patients under 65 years of age pose unique challenges, requiring optimal treatment strategies to preserve joint anatomy. This study primarily aimed to identify comorbid risk factors contributing to conversion surgery to total hip replacement (THR) due to avascular necrosis (AVN). This single-center, retrospective study included 160 patients (mean age = 50 ± 12 years, 78 males), followed up for an average of 10 years (range: 1-14 years). Fracture classifications were Garden 1 (N = 67), Garden 2 (N = 33), Garden 3 (N = 42), and Garden 4 (N = 19). Surgical procedures included Cannulated Hip Screws (CHS, N = 75), Femoral Neck System (FNS, N = 69), and Dynamic Hip Screw (DHS, N = 17). THR was required for 14 patients (8.7%) due to AVN. The mean age at conversion was 52.76 ± 15 years, with an average time to conversion of 22.2 months (range: 2-132 months). Univariate analysis identified fracture displacement (Garden 3-4), gender, smoking status, and diabetes mellitus as significant predictors for conversion surgery. Surgical method showed a trend toward significance (p = 0.08). A multivariate binary logistic regression model, including fracture displacement, gender, and smoking status as predictors, explained 45% of the variance in conversion to THR (p < 0.01). This study underscores the importance of assessing comorbid risk factors in younger patients with intracapsular femoral neck fractures. Identifying and addressing these factors may enhance the overall management of femoral neck fractures in this population.

摘要

65岁以下患者的囊内髋部骨折带来了独特的挑战,需要优化治疗策略以保留关节解剖结构。本研究主要旨在确定因缺血性坏死(AVN)导致全髋关节置换术(THR)转换手术的合并危险因素。这项单中心回顾性研究纳入了160例患者(平均年龄=50±12岁,78例男性),平均随访10年(范围:1 - 14年)。骨折分类为Garden 1型(N = 67)、Garden 2型(N = 33)、Garden 3型(N = 42)和Garden 4型(N = 19)。手术方式包括空心钉内固定(CHS,N = 75)、股骨颈系统(FNS,N = 69)和动力髋螺钉(DHS,N = 17)。14例患者(8.7%)因AVN需要进行THR。转换时的平均年龄为52.76±15岁,平均转换时间为22.2个月(范围:2 - 132个月)。单因素分析确定骨折移位(Garden 3 - 4型)、性别、吸烟状况和糖尿病是转换手术的显著预测因素。手术方式显示出显著趋势(p = 0.08)。一个多因素二元逻辑回归模型,包括骨折移位、性别和吸烟状况作为预测因素,解释了转换为THR的45%的方差(p < 0.01)。本研究强调了评估年轻囊内股骨颈骨折患者合并危险因素的重要性。识别并处理这些因素可能会改善该人群股骨颈骨折的整体管理。

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本文引用的文献

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Femoral neck fractures in non-geriatric patients: femoral neck system versus cannulated cancellous screw.非老年患者的股骨颈骨折:股骨颈系统与空心松质骨螺钉。
BMC Musculoskelet Disord. 2023 Jan 26;24(1):70. doi: 10.1186/s12891-023-06140-3.
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Global Research Status and Trends of Femoral Neck Fracture Over the Past 27 Years: A Historical Review and Bibliometric Analysis.过去27年股骨颈骨折的全球研究现状与趋势:历史回顾与文献计量分析
Front Surg. 2022 Jun 14;9:875040. doi: 10.3389/fsurg.2022.875040. eCollection 2022.
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Dynamic locking plate vs. cannulated cancellous screw for displaced intracapsular hip fracture: A comparative study.
动力锁定钢板与空心松质骨螺钉治疗移位型髋关节囊内骨折的对比研究
J Orthop. 2021 Feb 12;24:15-18. doi: 10.1016/j.jor.2021.02.008. eCollection 2021 Mar-Apr.
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Factors Associated With Revision Surgery After Internal Fixation of Hip Fractures.髋部骨折内固定术后翻修手术的相关因素
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Three-year outcomes of intracapsular femoral neck fractures fixed with sliding hip screws in adults aged under sixty-five years.六十五岁以下成年人采用滑动髋螺钉固定的股骨颈囊内骨折的三年预后
Injury. 2016 Nov;47(11):2495-2500. doi: 10.1016/j.injury.2016.09.013. Epub 2016 Sep 6.
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Long-Term Outcomes Following Reduction and Fixation of Displaced Subcapital Hip Fractures in the Young Elderly.年轻老年人移位型股骨颈骨折复位固定后的长期疗效
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