Zhang Shaowei
Department of Cardiothoracic Surgery, Pingdingshan Medical District, 989th Hospital of Joint Logistics Support Force, Pingdingshan 467021, China.
Zhongguo Fei Ai Za Zhi. 2024 Dec 20;27(12):947-955. doi: 10.3779/j.issn.1009-3419.2024.106.31.
Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common primary pulmonary lymphoma, which is an indolent B-cell lymphoma thought to originate from marginal zone B cells. Its pathophysiology is closely related to chronic antigenic stimulation, regardless of whether the antigens are auto-antigens or of microbial origin. Due to its nonspecific clinical presentation and low prevalence, pulmonary MALT lymphoma is often misdiagnosed. The disease is slow-growing, and different treatments have shown good efficacy, but its optimal treatment is somewhat controversial. This paper reviews the epidemiology, pathogenesis, clinical manifestations, computed tomography (CT) features, pathological diagnosis, treatment and prognosis of pulmonary MALT lymphoma, providing reference for clinicians to further understanding of the disease. .
黏膜相关淋巴组织(MALT)淋巴瘤是最常见的原发性肺淋巴瘤,是一种惰性B细胞淋巴瘤,被认为起源于边缘区B细胞。其病理生理学与慢性抗原刺激密切相关,无论抗原是自身抗原还是微生物来源。由于其临床表现不具特异性且发病率低,肺MALT淋巴瘤常被误诊。该疾病生长缓慢,不同的治疗方法已显示出良好疗效,但其最佳治疗方案仍存在一定争议。本文综述了肺MALT淋巴瘤的流行病学、发病机制、临床表现、计算机断层扫描(CT)特征、病理诊断、治疗及预后,为临床医生进一步了解该疾病提供参考。