Klimowicz Karolina, Dąbrowska Marta, Grabczak Elżbieta M, Białek-Gosk Katarzyna, Truba Olga, Rybka-Frączek Aleksandra, Paplińska-Goryca Magdalena, Nejman-Gryz Patrycja, Cyran Agata, Krenke Rafał
Department of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.
Department of Pathology, Medical University of Warsaw, Warsaw, Poland.
ERJ Open Res. 2025 Feb 17;11(1). doi: 10.1183/23120541.00571-2024. eCollection 2025 Jan.
A chronic cough (CC) is reported in 4-10% of the adult population and negatively affects quality of life [1-5]. Diagnosing and managing CC is challenging [3-5]. Initial evaluation typically includes chest radiography, spirometry, blood cell count (to detect blood eosinophils) and exhaled nitric oxide fraction, if available [4, 5]. Further diagnostic tests are warranted if clinical symptoms and basic tests cannot identify the cause of CC. Secondary diagnostic tests include oesophageal manometry or pH/impedance monitoring, induced sputum for eosinophils, laryngoscopy, bronchial provocation challenge, chest computed tomography (CT) and bronchoscopy [3-5].
据报道，4%至10%的成年人口患有慢性咳嗽（CC），这对生活质量有负面影响[1-5]。诊断和管理CC具有挑战性[3-5]。初始评估通常包括胸部X光检查、肺功能测定、血细胞计数（以检测血液嗜酸性粒细胞）以及呼出一氧化氮分数（若可行）[4,5]。如果临床症状和基础检查无法确定CC的病因，则需要进一步的诊断测试。二级诊断测试包括食管测压或pH/阻抗监测、诱导痰嗜酸性粒细胞检测、喉镜检查、支气管激发试验、胸部计算机断层扫描（CT）和支气管镜检查[3-5]。
