Murhabazi Bashombwa Augustin, Tchio-Nighie Ketina Hirma, Nanfak Aude, Buh Nkum Collins, Nguemnang Nguemnang Willy Armand, Fri Kami Rosine, Guenou Etienne, Ateudjieu Jerome
Faculty of Medicine, Université de Kaziba, Kaziba, Democratic Republic of Congo.
Department of Health Research, M.A. SANTE (Meilleur Accès aux soins de Santé), Yaoundé, Cameroon.
Pediatric Health Med Ther. 2025 Feb 12;16:35-45. doi: 10.2147/PHMT.S497787. eCollection 2025.
Vaccination is one of the most effective and efficient health interventions for reducing morbidity and mortality from infectious diseases, particularly in sub-Saharan Africa. Understanding the determinants of access to vaccines can help improve immunization coverage and control vaccine-preventable diseases. The aim of this study was to explore the contribution of certain determinants to access to pentavalent 3 in children aged 0-23 months in Cameroon via demographic and health survey data.
This was a cross-sectional nested case‒control study in which children aged 0-23 months were selected via cluster random sampling in households in the 10 regions of Cameroon. Secondary data from the Demographic and Health Survey, which was conducted in Cameroon from 2017-2018, were used. Univariate and multivariate logistic models were used to analyze the determinants of access to the pentavalent 3 vaccine.
The vaccination coverage of the pentavalent 3 vaccine (P3V) among children aged 0-23 months was 69.5%. The access to the P3V with Christian religion, compared with non-Christian experienced 63% of P3V (adjusted Odds ratio (AOR)=1.63, 95% CI, [1.22-2.17], p=0.001). Compared with those living in other regions in Cameron, those living in the northern regions of Cameroon were observed 37% less likely to have access to P3V (AOR=AOR=0.63, 95% CI, [0.44-0.87], p=0.006), while mother's marital status (married) compared with unmarried mothers were 37% more likely to experience access to P3V (AOR=1.37, 95% CI, [1.04-1.81], p=0.024). Relative to subjects with less education, those with at least secondary or higher education were 92% more likely to have access to P3V, (AOR=1.92, 95% CI [1.47-2.51], p<0.001), while those with cell phone experienced 44% increased access to P3V, (AOR=1.44, 95% CI, [1.17-1.78], p=0.001).
Access to the pentavalent 3 vaccine in Cameroon does not meet national targets and is affected by various socio-demographic factors, including region of residence, religion, educational attainment, maternal marital status, and cell phone ownership.
疫苗接种是降低传染病发病率和死亡率最有效且高效的健康干预措施之一,在撒哈拉以南非洲地区尤为如此。了解影响疫苗接种可及性的决定因素有助于提高免疫覆盖率并控制疫苗可预防疾病。本研究旨在通过人口与健康调查数据,探究某些决定因素对喀麦隆0至23个月儿童接种五价疫苗3的影响。
这是一项横断面巢式病例对照研究,通过整群随机抽样在喀麦隆10个地区的家庭中选取0至23个月的儿童。使用了2017 - 2018年在喀麦隆进行的人口与健康调查的二手数据。采用单变量和多变量逻辑模型分析五价疫苗3接种可及性的决定因素。
0至23个月儿童中五价疫苗3(P3V)的接种覆盖率为69.5%。与非基督教徒相比,基督教儿童接种P3V的比例为63%(调整优势比(AOR)=1.63,95%置信区间,[1.22 - 2.17],p = 0.001)。与生活在喀麦隆其他地区的儿童相比,生活在喀麦隆北部地区的儿童接种P3V的可能性低37%(AOR = 0.63,95%置信区间,[0.44 - 0.87],p = 0.006),而母亲已婚的儿童相比未婚母亲的儿童接种P3V的可能性高37%(AOR = 1.37,95%置信区间,[1.04 - 1.81],p = 0.024)。与受教育程度较低的受试者相比,至少接受过中等或更高教育的受试者接种P3V的可能性高92%(AOR = 1.92,95%置信区间[1.47 - 2.51],p < 0.001),而拥有手机的儿童接种P3V的可及性增加44%(AOR = 1.44,95%置信区间,[1.17 - 1.78],p = 0.001)。
喀麦隆五价疫苗3的接种可及性未达到国家目标,且受到多种社会人口因素的影响,包括居住地区、宗教、教育程度、母亲婚姻状况和手机拥有情况。