Wills Mélissa V, Barajas-Gamboa Juan S, Romero-Velez Gustavo, Strong Andrew, Navarrete Salvador, Corcelles Ricard, Abril Carlos, Pantoja Juan Pablo, Guerron Alfredo D, Rodriguez John, Kroh Matthew, Dang Jerry
Cleveland Clinic Lerner College of Medicine, Cleveland Clinic Foundation, Case Western Reserve University, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Obes Surg. 2025 Mar;35(3):725-732. doi: 10.1007/s11695-025-07697-9. Epub 2025 Feb 18.
Endoscopic gastric pouch plications (EGPP) have emerged as a novel approach for managing weight-related issues and postoperative complications following bariatric surgery. However, safety for these revisions remains limited. This study aims to evaluate the 30-day rate of serious complications and mortality associated with EGPP using the MBSAQIP database. METHODS: A retrospective analysis of the MBSAQIP database from 2020 to 2022 was conducted, focusing on patients undergoing EGPP. The primary outcomes were 30-day serious complications and mortality.
The study included 1474 patients. Recurrent weight gain was the most common indication for EGPP (71.9%), followed by suboptimal initial weight loss (15.1%), dumping syndrome (5.5%), reflux (4.1%), gastrointestinal tract fistula (1.0%), and others (0.9%). The mean operative time was 41.2 ± 35.2 min, with a mean hospital stay of 0.4 ± 0.7 days. Postoperative complications included 30-day readmissions (3.1%), serious complications (3.3%), 30-day interventions (2.5%), bleeding (0.8%), and reoperations (0.4%). The mortality rate was 0%. Multivariable analysis identified GERD as an independent predictor of serious complications (OR 1.79, 95% CI 0.98 to 3.2, p = 0.05) when adjusting for various factors.
EGPP is an uncommon procedure with only 1474 cases reported, primarily indicated for weight recurrence. It appears to be a relatively safe alternative to surgical revision. However, further research is needed to assess its efficacy and compare it to corresponding surgical revisions.
内镜胃囊折叠术(EGPP)已成为一种用于处理减肥手术后体重相关问题和术后并发症的新方法。然而,这些翻修手术的安全性仍然有限。本研究旨在使用MBSAQIP数据库评估与EGPP相关的30天严重并发症发生率和死亡率。
对2020年至2022年的MBSAQIP数据库进行回顾性分析,重点关注接受EGPP的患者。主要结局为30天严重并发症和死亡率。
该研究纳入了1474例患者。体重再次增加是EGPP最常见的适应证(71.9%),其次是初始体重减轻不理想(15.1%)、倾倒综合征(5.5%)、反流(4.1%)、胃肠道瘘(1.0%)和其他情况(0.9%)。平均手术时间为41.2±35.2分钟,平均住院时间为0.4±0.7天。术后并发症包括30天再入院(3.1%)、严重并发症(3.3%)、30天干预(2.5%)、出血(0.8%)和再次手术(0.4%)。死亡率为0%。多变量分析在调整各种因素后确定胃食管反流病是严重并发症的独立预测因素(OR 1.79,95%CI 0.98至3.2,p = 0.05)。
EGPP是一种不常见的手术,仅报告了1474例病例,主要用于体重复发。它似乎是手术翻修的一种相对安全的替代方法。然而,需要进一步研究来评估其疗效并与相应的手术翻修进行比较。