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溴隐亭诱导催乳素瘤细胞内质网膜的去除。

Bromocriptine-induced removal of endoplasmic membranes from prolactinoma cells.

作者信息

Landolt A M, Osterwalder V, Landolt T A

出版信息

Experientia. 1985 May 15;41(5):640-2. doi: 10.1007/BF02007698.

DOI:10.1007/BF02007698
PMID:3996537
Abstract

Adenomatous prolactin cells lose 39% of their cytoplasm volume within 7 days after the beginning of bromocriptine treatment. A simultaneous reduction of the rough-surfaced endoplasmic reticulum and the Golgi apparatus occurs. Their membranes are removed by rapid transport along the secretory pathway to the cell surface and to lysosomal destruction.

摘要

在开始使用溴隐亭治疗后的7天内,腺瘤性催乳素细胞的细胞质体积减少了39%。同时,糙面内质网和高尔基体也出现减少。它们的膜通过沿分泌途径快速转运至细胞表面并被溶酶体破坏而被清除。

相似文献

1
Bromocriptine-induced removal of endoplasmic membranes from prolactinoma cells.溴隐亭诱导催乳素瘤细胞内质网膜的去除。
Experientia. 1985 May 15;41(5):640-2. doi: 10.1007/BF02007698.
2
Immunohistochemical, electron microscopic and morphometric studies of estrogen-induced rat prolactinomas after bromocriptine treatment.
Virchows Arch B Cell Pathol Incl Mol Pathol. 1987;53(2):89-96. doi: 10.1007/BF02890229.
3
Cytosuppressive effect of bromocriptine on human prolactinomas: stereological analysis of ultrastructural alterations with special reference to secretory granules.溴隐亭对人催乳素瘤的细胞抑制作用:超微结构改变的体视学分析,特别涉及分泌颗粒
Cancer Res. 1986 Mar;46(3):1507-12.
4
Bromocriptine therapy as pre-operative adjunct of non-functional pituitary macroadenomas.
Acta Endocrinol (Copenh). 1985 Apr;108(4):445-50. doi: 10.1530/acta.0.1080445.
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Ultrastructural morphometry of sparsely granulated prolactin cell adenomas of the human pituitary.人垂体稀疏颗粒型催乳素细胞腺瘤的超微结构形态计量学
Acta Endocrinol (Copenh). 1978 Nov;89(3):521-9. doi: 10.1530/acta.0.0890521.
6
[Pathological changes of prolactinomas treated with bromocriptine].
No Shinkei Geka. 1982 Jun;10(6):619-27.
7
Bromocriptine reduces the size of cells in prolactin-secreting pituitary adenomas.溴隐亭可减小分泌催乳素的垂体腺瘤中的细胞大小。
Experientia. 1983 Jun 15;39(6):625-6. doi: 10.1007/BF01971131.
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Size reduction of a large prolactinoma by bromocriptine treatment. Report of a case.溴隐亭治疗使巨大泌乳素瘤缩小。病例报告。
Neurol Med Chir (Tokyo). 1981 Jan;21(1):127-30. doi: 10.2176/nmc.21.127.
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Ultrastructural localization of prolactin in estrogen-induced prolactinoma of the rat pituitary. Experimental models for the human prolactinomas and the effects of bromocriptine.催乳素在雌激素诱导的大鼠垂体催乳素瘤中的超微结构定位。人类催乳素瘤的实验模型及溴隐亭的作用。
Acta Pathol Jpn. 1986 Aug;36(8):1131-7. doi: 10.1111/j.1440-1827.1986.tb02834.x.
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Ultrastructural morphometry of prolactin secreting adenomas treated with dopamine agonists.多巴胺激动剂治疗的催乳素分泌性腺瘤的超微结构形态计量学
Pathol Res Pract. 1986 Jun;181(3):280-90. doi: 10.1016/S0344-0338(86)80104-2.

引用本文的文献

1
Diagnosis and drug therapy of prolactinoma.泌乳素瘤的诊断与药物治疗
Drugs. 1996 Jun;51(6):954-65. doi: 10.2165/00003495-199651060-00004.
2
Human pituitary adenomas. Recent advances in morphological studies.人类垂体腺瘤。形态学研究的最新进展。
J Endocrinol Invest. 1990 May;13(5):435-54. doi: 10.1007/BF03350700.

本文引用的文献

1
Prolactinomas and optic nerve compression: disappearance of suprasellar extension and visual recovery after two weeks bromocriptine treatment.
Horm Res. 1981;14(3):141-7. doi: 10.1159/000179381.
2
Dopaminergic inhibition of prolactin synthesis and prolactin messenger RNA accumulation in cultured pituitary cells.多巴胺能抑制培养垂体细胞中催乳素的合成及催乳素信使核糖核酸的积累。
J Biol Chem. 1980 Sep 10;255(17):8092-7.
3
Bromocriptine reduces the size of cells in prolactin-secreting pituitary adenomas.溴隐亭可减小分泌催乳素的垂体腺瘤中的细胞大小。
Experientia. 1983 Jun 15;39(6):625-6. doi: 10.1007/BF01971131.
4
Human prolactin-producing adenomas and bromocriptine: a histological, immunocytochemical, ultrastructural, and morphometric study.人催乳素分泌性腺瘤与溴隐亭:一项组织学、免疫细胞化学、超微结构及形态计量学研究。
J Clin Endocrinol Metab. 1982 Dec;55(6):1178-83. doi: 10.1210/jcem-55-6-1178.
5
Multiple pathways of exocytosis, endocytosis, and membrane recycling: validation of a Golgi route.胞吐、胞吞和膜循环的多种途径:高尔基体途径的验证
Fed Proc. 1983 May 15;42(8):2407-13.
6
Transcriptional regulation of the prolactin gene by ergocryptine and cyclic AMP.麦角隐亭和环磷酸腺苷对催乳素基因的转录调控
Nature. 1981 Nov 5;294(5836):94-7. doi: 10.1038/294094a0.
7
Passage of an integral membrane protein, the vesicular stomatitis virus glycoprotein, through the Golgi apparatus en route to the plasma membrane.一种整合膜蛋白,即水泡性口炎病毒糖蛋白,在前往质膜的途中穿过高尔基体。
Proc Natl Acad Sci U S A. 1981 Mar;78(3):1746-50. doi: 10.1073/pnas.78.3.1746.
8
Injectable bromocriptine to treat acute, oestrogen-induced swelling of invasive prolactinoma.注射用溴隐亭治疗侵袭性泌乳素瘤的急性雌激素诱导性肿胀。
Lancet. 1984 Jul 14;2(8394):111. doi: 10.1016/s0140-6736(84)90287-3.
9
Biogenesis of endoplasmic reticulum membranes. I. Structural and chemical differentiation in developing rat hepatocyte.内质网膜的生物发生。I. 发育中大鼠肝细胞的结构和化学分化
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Practical stereological methods for morphometric cytology.形态计量细胞学的实用体视学方法。
J Cell Biol. 1966 Jul;30(1):23-38. doi: 10.1083/jcb.30.1.23.