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通过食用含粉末的功能性食品对韩国中年人群肠道状况和临床因素的影响:前瞻性、随机、开放标签和对照比较试验。

Effects of the Intestinal Status and Clinical Factors of Korean Middle-Aged People Through the Consumption of Functional Foods Containing Powder: Prospective, Randomized, Open-Label, and Control Comparative Trial.

作者信息

Son Eun-Ha, Jung Dong Hoon, Shin Hyeri, Lee SangHwa, Kim YoungSun, Lim Hee-Sook

机构信息

Department of Gerontology, AgeTech-Service Convergence Major, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea.

National Medical Center, National Institute of Dementia, Seoul 04564, Korea.

出版信息

Clin Nutr Res. 2025 Jan 22;14(1):7-16. doi: 10.7762/cnr.2025.14.1.7. eCollection 2025 Jan.

DOI:10.7762/cnr.2025.14.1.7
PMID:39968271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11832288/
Abstract

This study aimed to evaluate the effects of functional foods containing powder on gut health and clinical indicators in middle-aged and older adults. Participants were randomly assigned to either the intervention group (n = 24) or control group (n = 26), and assessments including anthropometric measurements, blood analyses, and dietary intake surveys were conducted. The intervention group consumed functional foods containing powder twice daily for 8 weeks. No statistically significant differences were observed in the gut environmental parameters between the 2 groups. However, reductions in waist circumference (p < 0.021), abdominal obesity (p < 0.006), and triglyceride levels (p < 0.016) in the intervention group were statistically significant. Additionally, an analysis of nutrient intake from meals other than the intervention food revealed a significant increase in dietary fiber (p < 0.043), vitamin B1 (p < 0.027), and folic acid (p < 0.006) intake in the intervention group. Although the intervention improved the selection of body composition and blood parameters, it failed to produce significant changes in constipation outcomes or gut environmental parameters among participants with constipation. In conclusion, the consumption of powder-based functional foods resulted in limited yet meaningful improvements, specifically in reducing waist circumference and triglyceride levels.

摘要

本研究旨在评估含 粉功能性食品对中老年人肠道健康和临床指标的影响。参与者被随机分为干预组(n = 24)或对照组(n = 26),并进行了包括人体测量、血液分析和饮食摄入调查在内的评估。干预组每天食用含 粉的功能性食品两次,持续8周。两组之间的肠道环境参数未观察到统计学上的显著差异。然而,干预组的腰围(p < 0.021)、腹部肥胖(p < 0.006)和甘油三酯水平(p < 0.016)的降低具有统计学意义。此外,对干预食品以外的餐食营养摄入分析显示,干预组的膳食纤维(p < 0.043)、维生素B1(p < 0.027)和叶酸(p < 0.006)摄入量显著增加。尽管干预改善了身体成分和血液参数的选择,但在便秘参与者中,便秘结局或肠道环境参数未产生显著变化。总之,食用基于 粉的功能性食品带来了有限但有意义的改善,特别是在减少腰围和甘油三酯水平方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262b/11832288/164acb393f78/cnr-14-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262b/11832288/164acb393f78/cnr-14-7-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/262b/11832288/164acb393f78/cnr-14-7-g001.jpg

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本文引用的文献

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Dietary Supplementation of Polysaccharides Alleviate Nutritional Obesity in Mice via Regulating Inflammatory Response and Lipid Metabolism.膳食补充多糖通过调节炎症反应和脂质代谢减轻小鼠营养性肥胖。
Foods. 2022 Mar 24;11(7):942. doi: 10.3390/foods11070942.
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Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysis.根据罗马标准,全球功能性便秘的患病率:系统评价和荟萃分析。
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Review on as a Functional Food: Growth, Chemical Composition, and Biological Activities.作为功能性食品的[具体名称未给出]综述:生长、化学成分及生物活性
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