School of Pharmacy, Hainan Medical University, Haikou, Hainan 570100, China; Hainan Provincial Key Laboratory of R & D on Tropical Herbs, Haikou, Hainan 570100, China; Key Laboratory of Tropical Translational Medicine of Ministry of Education, Haikou, Hainan 570100, China.
Department of Food Science, Cornell University, Ithaca, NY 14853-7201, USA.
Int J Biol Macromol. 2020 May 1;150:102-113. doi: 10.1016/j.ijbiomac.2020.02.054. Epub 2020 Feb 7.
Auricularia mushrooms are known for their bioactive compounds, mostly polysaccharides, which have numerous biological activities, such as antioxidant, antitumor, immunomodulatory, hyperlipidemic, antidiabetic, anticoagulant and hepatoprotective effects. Over the past decades, there has been a consistent focus on the isolation, chemical properties and bioactivities of polysaccharides from Auricularia. This review will cover what is known about Auricularia polysaccharides (AP) especially for several common species, including A. auricula-judae, A. auricula, A. polytricha, and A. cornea var. Li. The isolation and purifications, structural characterizations, chemical modifications, and biological activities of these AP and their derivatives will be discussed, thus to provide a foundation for the further investigation, production, and application of AP as functional foods and therapeutic agents.
银耳菇以其生物活性化合物而闻名，主要是多糖，具有多种生物活性，如抗氧化、抗肿瘤、免疫调节、降血脂、降血糖、抗凝和保肝作用。在过去的几十年中，人们一直关注银耳多糖（AP）的分离、化学性质和生物活性。本文综述了银耳多糖（AP）的研究进展，特别是几种常见种，包括黑木耳、黑木耳、毛木耳和黄背木耳。讨论了这些 AP 及其衍生物的分离纯化、结构特征、化学修饰和生物活性，为 AP 作为功能性食品和治疗剂的进一步研究、生产和应用提供了基础。
