Damani Janhavi J, Kris-Etherton Penny M, Lichtenstein Alice H, Matthan Nirupa R, Sabaté Joan, Li Zhaoping, Reboussin David, Petersen Kristina S
Department of Nutritional Sciences The Pennsylvania State University University Park PA.
Jean Mayer USDA Human Nutrition Research Center on Aging Tufts University Boston MA.
J Am Heart Assoc. 2025 Mar 4;14(5):e039130. doi: 10.1161/JAHA.124.039130. Epub 2025 Feb 19.
The effect of single food-based dietary interventions on the American Heart Association's cardiovascular health score, Life's Essential 8 (LE8), is unclear. The aim of this study was to examine the effect of daily avocado intake for 26 weeks on LE8 in adults with abdominal obesity.
An ancillary analysis including participants (n=969; aged 51±14 years) from the HAT (Habitual Diet and Avocado Trial), a randomized controlled trial, was conducted. The Avocado-Supplemented Diet Group was provided with 1 avocado per day, and the Habitual Diet Group was instructed to maintain their usual diet. LE8 component scores (diet, physical activity, nicotine exposure, sleep health, body mass index, blood lipids, blood glucose, and blood pressure) were calculated using a modified American Heart Association algorithm. The LE8 score was calculated as the unweighted average of each component (range, 0-100 points). Between-group differences in the 26-week change in LE8 were assessed using general linear models. No significant between-group difference in the 26-week change in the LE8 score from baseline was observed (0.79 points [95% CI, -0.41 to 2.00]). However, avocado intake increased the LE8 component scores for diet (3.53 points [95% CI, 1.38-5.68]), sleep health (3.20 points [95% CI, 0.38-6.02]), and blood lipids (3.46 points [95% CI, 1.03-5.90]) compared with the Habitual Diet Group.
Intake of 1 avocado per day for 26 weeks did not significantly affect the total cardiovascular health score in US adults with abdominal obesity. However, diet quality, sleep health, and blood lipids improved with daily avocado intake.
URL: https://www.clinicaltrials.gov; Unique identifier: NCT03528031.
基于单一食物的饮食干预对美国心脏协会心血管健康评分（生命八大要素，LE8）的影响尚不清楚。本研究旨在探讨在腹部肥胖的成年人中，连续26周每日摄入牛油果对LE8的影响。
进行了一项辅助分析，纳入了来自随机对照试验“习惯饮食与牛油果试验”（HAT）的参与者（n = 969；年龄51±14岁）。牛油果补充饮食组每天提供1个牛油果，习惯饮食组被要求维持其平常饮食。使用改良的美国心脏协会算法计算LE8各组成部分的得分（饮食、身体活动、尼古丁暴露、睡眠健康、体重指数、血脂、血糖和血压）。LE8得分计算为各组成部分的未加权平均值（范围为0 - 100分）。使用一般线性模型评估两组在26周内LE8从基线变化的组间差异。未观察到两组在26周内LE8得分相对于基线的变化存在显著组间差异（0.79分[95%CI，-0.41至2.00]）。然而，与习惯饮食组相比，摄入牛油果使饮食（3.53分[95%CI，1.38 - 5.68]）、睡眠健康（3.20分[95%CI，0.38 - 6.02]）和血脂（3.46分[95%CI，1.03 - 5.90]）的LE8组成部分得分有所提高。
在腹部肥胖的美国成年人中，连续26周每天摄入1个牛油果并未显著影响总体心血管健康评分。然而，每日摄入牛油果可改善饮食质量、睡眠健康和血脂。
