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钬激光前列腺切除术对原发性膀胱颈梗阻手术效果的影响。

Effect of holmium laser prostatectomy on surgical outcomes of primary bladder neck obstruction.

作者信息

Lee Hyomyoung, Jeong Hyun Ju, Choo Min Soo, Cho Sung Yong, Jeong Seong Jin, Oh Seung-June

机构信息

Department of Urology, Seoul National University Hospital, 101 Daehak-no, Jongno-gu, Seoul, 03080, Republic of Korea.

Department of Urology, Seoul National University College of Medicine, Seoul, Republic of Korea.

出版信息

BMC Urol. 2025 Feb 19;25(1):33. doi: 10.1186/s12894-025-01693-y.

Abstract

BACKGROUND

The purpose of this study is to evaluate the efficacy and safety of holmium laser prostatectomy in patients diagnosed with primary bladder neck obstruction (PBNO), compared with patients with benign prostatic hyperplasia (BPH).

METHODS

We analyzed the databases of patients who underwent a holmium laser prostatectomy or enucleation of the prostate for PBNO and BPH between January 2018 and August 2022. PBNO was diagnosed primarily based on cystourethroscopic findings. Patients were followed up according to a regular protocol at 2 weeks, 3 mo, and 6 mo postoperatively.

RESULTS

In total, 28 and 447 patients with PBNO and BPH, respectively, were identified. Preoperative urodynamic studies showed that detrusor underactivity was significantly more prevalent in the PBNO group (78.6%) than in the BPH group (57.5%) (p < 0.01). Both PBNO and BPH groups showed significant improvements in the total International Prostate Symptom Score, Overactive Bladder Symptom Score, and maximum flow rate at 6 mo postoperatively compared with the preoperative values (p < 0.01). Subjective satisfaction 6 mo after operation was not significantly different between the PBNO and BPH groups (p > 0.05). Complications in the PBNO group included recatheterization (n = 1, 3.5%), with no patients requiring blood transfusion or transurethral coagulation.

CONCLUSIONS

Holmium laser prostatectomy was effective and safe for patients with PBNO, with elevated subjective patient satisfaction.

摘要

背景

本研究的目的是评估钬激光前列腺切除术在诊断为原发性膀胱颈梗阻(PBNO)患者中的疗效和安全性,并与良性前列腺增生(BPH)患者进行比较。

方法

我们分析了2018年1月至2022年8月期间因PBNO和BPH接受钬激光前列腺切除术或前列腺摘除术的患者数据库。PBNO主要根据膀胱尿道镜检查结果进行诊断。术后2周、3个月和6个月按照常规方案对患者进行随访。

结果

总共分别确定了28例PBNO患者和447例BPH患者。术前尿动力学研究表明,PBNO组逼尿肌活动不足的发生率(78.6%)显著高于BPH组(57.5%)(p<0.01)。与术前值相比,PBNO组和BPH组术后6个月的国际前列腺症状总分、膀胱过度活动症症状评分和最大尿流率均有显著改善(p<0.01)。PBNO组和BPH组术后6个月的主观满意度无显著差异(p>0.05)。PBNO组的并发症包括再次插管(n = 1,3.5%),没有患者需要输血或经尿道凝血。

结论

钬激光前列腺切除术对PBNO患者有效且安全,患者主观满意度较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3336/11837319/524a2ad13cea/12894_2025_1693_Fig1_HTML.jpg

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