Tenkanen L, Hakulinen T, Hakama M, Saxén E
Int J Cancer. 1985 May 15;35(5):637-42. doi: 10.1002/ijc.2910350511.
To study possible causes of the high lung cancer incidence among Finnish males, the Finnish Cancer Registry and the Cancer Registry of Norway in 1962 performed a population survey covering smoking habits, occupational and residential history and, in Finland, sauna habits. The cohort of 4,475 Finnish men has now been followed up for incidence of lung cancer in 1964-1979. The relative importance of 3 factors--sauna baths, occupational exposure to dust, and migration to urban areas--was studied in different smoking categories. Among smokers of greater than or equal to 25 g/day, takers of frequent saunas (more than once a week) displayed some excess risk (RR 1.7). In smokers an increased risk was also found among those exposed to dust (RR 1.3), and those who had migrated to urban areas (RR 1.8, when compared to native urban population). Dust exposure and migration factors act synergistically with smoking. Migration was the only factor apart from smoking to show a substantial population-attributable risk, which amounted to 10%.
为研究芬兰男性肺癌高发的可能原因,芬兰癌症登记处和挪威癌症登记处于1962年开展了一项人口调查,内容涵盖吸烟习惯、职业和居住史,在芬兰还包括桑拿习惯。现已对4475名芬兰男性队列随访其1964 - 1979年肺癌发病率。在不同吸烟类别中研究了三个因素——桑拿浴、职业性粉尘接触和移居城市地区——的相对重要性。在每日吸烟量大于或等于25克的人群中,经常洗桑拿的人(每周不止一次)显示出一定的额外风险(相对危险度1.7)。在吸烟者中,接触粉尘者(相对危险度1.3)和移居城市地区者(与城市本地人口相比相对危险度1.8)也发现风险增加。粉尘接触和移居因素与吸烟存在协同作用。移居是除吸烟外唯一显示出相当大的人群归因危险度的因素,达10%。