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吸烟是否足以解释芬兰和挪威肺癌发病率的巨大差异?

Is smoking sufficient to explain the large difference in lung cancer incidence between Finland and Norway?

作者信息

Hakulinen T, Magnus K, Tenkanen L

出版信息

Scand J Soc Med. 1987;15(1):3-10. doi: 10.1177/140349488701500102.

Abstract

In the 1960s, lung cancer among Finnish men was about 3.5 times as common as among Norwegian men. A study by Pedersen et al. in 1962 indicated that the difference in contemporary smoking habits could account for only part of the difference in lung cancer incidence in men between the countries. In that study, smoking habits in Finland and Norway were investigated via interviews of 8,700 people from six areas of each country. For the present study the Finnish and Norwegian cancer registries have followed lung cancer morbidity in those areas. When the interval between the recording of smoking habits and lung cancer incidence was 15 years, after adjustment for age and smoking habits, the Finnish males had a relative risk between 1.1 and 1.6 compared with Norwegian men. The results suggest that, given a sufficiently long latency period, almost the entire difference between Finnish and Norwegian men could be attributed to smoking habits.

摘要

20世纪60年代,芬兰男性肺癌的发病率约为挪威男性的3.5倍。1962年,佩德森等人开展的一项研究表明,当时吸烟习惯的差异只能部分解释两国男性肺癌发病率的差异。在该研究中,通过对来自芬兰和挪威六个地区的8700人进行访谈,调查了这两个国家的吸烟习惯。在本研究中,芬兰和挪威的癌症登记机构对这些地区的肺癌发病率进行了跟踪。当吸烟习惯记录与肺癌发病率之间的间隔为15年时,在对年龄和吸烟习惯进行调整后,与挪威男性相比,芬兰男性的相对风险在1.1至1.6之间。结果表明,在潜伏期足够长的情况下,芬兰和挪威男性之间几乎所有的差异都可归因于吸烟习惯。

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