Katona G
Int J Clin Pharmacol Res. 1985;5(1):9-15.
The selection of the ideal anti-inflammatory drug is an important task bearing in mind some of the characteristics concerning its pharmacokinetics, mechanism of action, efficacy, tolerability, dosage, safety, presentation and route of administration, patient compliance and patient expectancy. The present paper deals with each of these topics, based on current knowledge of the different anti-inflammatory drugs and the more than 20 years experience in a great number of clinical trials with most of the best known non-hormonal anti-inflammatory compounds.
选择理想的抗炎药物是一项重要任务,需要考虑其药代动力学、作用机制、疗效、耐受性、剂量、安全性、剂型、给药途径、患者依从性和患者期望等一些特征。本文基于对不同抗炎药物的现有知识以及在大量临床试验中对大多数最知名的非激素抗炎化合物超过20年的经验,对上述每个主题进行了探讨。