Arnesen K
Int Ophthalmol. 1985 Mar;7(3-4):143-7. doi: 10.1007/BF00128360.
On the basis of two cases the relation between 'neurogenic' tumours (neurinomas, neurilemmomas, Schwannomas, neurofibromas) and malignant melanomas of the uvea is discussed with emphasis on the close association of both groups of neoplasms with the ciliary nerves. The great histopathological diversity between different cases of melanoma as well as within individual cases is also pointed out. On histological and cytological criteria it may be difficult to differentiate between the 'neurogenic' tumours and the highly differentiated, spindle cell variants of the melanomas. Since all these tumours are derived from the neural crest, they might be grouped under one common heading. It is postulated that 'neurogenic' tumours have been overdiagnosed to the disadvantage of the highly differentiated spindle cell melanomas.
基于两个病例，讨论了“神经源性”肿瘤（神经鞘瘤、神经膜瘤、施万瘤、神经纤维瘤）与葡萄膜恶性黑色素瘤之间的关系，重点强调了这两组肿瘤与睫状神经的密切关联。还指出了不同黑色素瘤病例之间以及单个病例内部存在的巨大组织病理学差异。根据组织学和细胞学标准，可能难以区分“神经源性”肿瘤与黑色素瘤的高分化梭形细胞变体。由于所有这些肿瘤均起源于神经嵴，它们可能可归为一个共同的类别。据推测，“神经源性”肿瘤被过度诊断，对高分化梭形细胞黑色素瘤不利。
