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梅奥测试驱动远程自我管理的基于网络的认知筛查量表在35至100岁有和没有认知障碍的成年人中的可用性。

Usability of the Mayo Test Drive remote self-administered web-based cognitive screening battery in adults aged 35-100 with and without cognitive impairment.

作者信息

Patel Jay S, Christianson Teresa J, Monahan Logan T, Frank Ryan D, Fan Winnie Z, Stricker John L, Kremers Walter K, Karstens Aimee J, Machulda Mary M, Fields Julie A, Hassenstab Jason, Jack Clifford R, Botha Hugo, Graff-Radford Jonathan, Petersen Ronald C, Stricker Nikki H

机构信息

Division of Neurocognitive Disorders, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.

Division of Biomedical Statistics and Informatics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.

出版信息

J Clin Exp Neuropsychol. 2025 Feb-Mar;47(1-2):67-89. doi: 10.1080/13803395.2025.2464633. Epub 2025 Feb 20.

Abstract

BACKGROUND

Mayo Test Drive (MTD): Mayo Test Development through Rapid Iteration, Validation and Expansion, is a web-based remote cognitive assessment platform for self-administered neuropsychological measures with previously demonstrated validity and reliability. We examined the usability of MTD and hypothesized that completion rates would be greater than 90%. We explored whether completion and participation rates differed by cognitive status and demographic factors.

METHODS

A total of 1,950 Mayo Clinic Study of Aging and Mayo Alzheimer's Disease Research Center participants (97% White, 99% Non-Hispanic) were invited to participate in this ancillary, uncompensated remote study. Most invitees were cognitively unimpaired (CU;  = 1,769; 90.7%) and 9.3% were cognitively impaired (CI;  = 181). Usability was objectively defined as the percentage of participants who completed a session after initiating a session for a given timepoint (i.e. completion rates).

RESULTS

Baseline session completion rates were 98.5% ( = 1199/1217 participants, mean age 71, SD = 12, range 35-100) and were comparable between CU (98.7%) and CI (95.0%) groups ( = .23). Completion rates did not significantly differ by age groups ( > .10) and remained high in individuals 80+ ( = 251, 97.3%). Participation rates were higher in the CU ( = 1142, 65.4%) versus CI ( = 57, 33.1%) group ( < .001); participants were younger and had more years of education (p's < .001). Adherence (i.e. retention) rate for a 7.5-month follow-up session was 89%. Average session duration was 16 min. Most participants used a personal computer (62.7%), followed by a smartphone (22.2%) or tablet (14.8%). Comments entered by 36.4% of participants reflected several themes including acceptability, face validity, usability, and comments informative for session context.

CONCLUSIONS

MTD demonstrated high usability as defined by completion rates in this research sample that includes a broad age range, though participation rates are lower in individuals with cognitive impairment. Results support good adherence at follow-up, feasibility through mean session duration, and acceptability based on qualitative analysis of participant comments.

摘要

背景

梅奥试驾(MTD):通过快速迭代、验证和扩展进行梅奥测试开发,是一个基于网络的远程认知评估平台,用于自我管理的神经心理学测量,此前已证明其有效性和可靠性。我们研究了MTD的可用性,并假设完成率将超过90%。我们探讨了完成率和参与率是否因认知状态和人口统计学因素而有所不同。

方法

共有1950名梅奥诊所衰老研究和梅奥阿尔茨海默病研究中心的参与者(97%为白人,99%为非西班牙裔)被邀请参加这项辅助性、无报酬的远程研究。大多数受邀者认知功能未受损(CU;=1769;90.7%),9.3%认知功能受损(CI;=181)。可用性被客观定义为在给定时间点启动会话后完成会话的参与者百分比(即完成率)。

结果

基线会话完成率为98.5%(=1199/1217名参与者,平均年龄71岁,标准差=12,范围35 - 100岁),在CU组(98.7%)和CI组(95.0%)之间具有可比性(=0.23)。完成率在不同年龄组之间没有显著差异(>0.10),80岁及以上个体的完成率仍然很高(=251,97.3%)。CU组(=1142,65.4%)的参与率高于CI组(=57,33.1%)(<0.001);参与者更年轻,受教育年限更多(p值<0.001)。7.5个月随访会话的依从性(即保留率)为89%。平均会话时长为16分钟。大多数参与者使用个人电脑(62.7%),其次是智能手机(22.2%)或平板电脑(14.8%)。36.4%的参与者输入的评论反映了几个主题,包括可接受性、表面效度、可用性以及对会话背景有参考价值的评论。

结论

在这个包括广泛年龄范围的研究样本中,MTD以完成率定义的可用性较高,尽管认知功能受损个体的参与率较低。结果支持随访时的良好依从性、通过平均会话时长体现的可行性以及基于对参与者评论的定性分析得出的可接受性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa80/12129114/5f146cb4235d/nihms-2056696-f0001.jpg

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