Dunsmore Victoria J, Ellis Charlotte, Drier Sarah, Waters Austin R, Fray Niasha, Stylianou Christina, Spencer Jennifer C, Reeder-Hayes Katherine E, Wheeler Stephanie B
Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA.
Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Cancer Causes Control. 2025 Jul;36(7):725-732. doi: 10.1007/s10552-025-01971-y. Epub 2025 Feb 20.
This study evaluates the implementation of the GETSET (Guiding Endocrine Therapy Success through Empowerment and Teamwork) pilot, a motivational interviewing (MI) intervention aimed at improving endocrine therapy (ET) adherence among patients with breast cancer.
Using the Consolidated Framework for Implementation Research (CFIR), qualitative interviews were conducted with site staff (N = 2), patients (N = 4), and counselors (N = 2).
The thematic analysis identified facilitators such as high-quality materials, ease of scheduling sessions, and effective communication among staff. However, barriers included lack of personalization and systemic issues like understaffing.
The study underscores the need to adapt implementation of behavioral interventions in a healthcare setting to improve ET adherence. As this was a process evaluation of a pilot study, future work should evaluate the barriers and facilitators to a larger clinical trial to identify if the same strategies should be refined.
本研究评估了GETSET(通过赋权和团队合作指导内分泌治疗成功)试点项目的实施情况,这是一项动机性访谈(MI)干预措施,旨在提高乳腺癌患者内分泌治疗(ET)的依从性。
采用实施研究综合框架(CFIR),对现场工作人员(N = 2)、患者(N = 4)和咨询师(N = 2)进行了定性访谈。
主题分析确定了一些促进因素,如高质量的材料、轻松的预约安排以及工作人员之间的有效沟通。然而,障碍包括缺乏个性化以及人员不足等系统性问题。
该研究强调了在医疗环境中调整行为干预措施的实施以提高ET依从性的必要性。由于这是一项试点研究的过程评估,未来的工作应评估更大规模临床试验的障碍和促进因素,以确定是否应完善相同的策略。