Key targets for small molecule drugs on the IGF1 signaling pathway.
作者信息
Werner Haim
机构信息
Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
出版信息
Future Med Chem. 2025 Apr;17(7):751-753. doi: 10.1080/17568919.2025.2470105. Epub 2025 Feb 20.
Abstract
摘要
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本文引用的文献
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The IGF1 Signaling Pathway: From Basic Concepts to Therapeutic Opportunities.IGF1 信号通路：从基础概念到治疗机会。
Int J Mol Sci. 2023 Oct 4;24(19):14882. doi: 10.3390/ijms241914882.
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Hallmarks of cancer: The insulin-like growth factors perspective.癌症的特征：胰岛素样生长因子视角
Front Oncol. 2022 Nov 21;12:1055589. doi: 10.3389/fonc.2022.1055589. eCollection 2022.
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Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease.社论：胰岛素样生长因子/胰岛素-胰岛素样生长因子结合蛋白轴在正常生理和疾病中的作用
Front Endocrinol (Lausanne). 2022 Apr 21;13:892140. doi: 10.3389/fendo.2022.892140. eCollection 2022.
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Investigational IGF1R inhibitors in early stage clinical trials for cancer therapy.在癌症治疗的早期临床试验中，研究性 IGF1R 抑制剂。
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Therapeutic Targeting of the IGF Axis.IGF 轴的治疗靶向。
Cells. 2019 Aug 14;8(8):895. doi: 10.3390/cells8080895.
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