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将区块链技术与人工智能相结合用于胫骨平台骨折的诊断。

Integrating blockchain technology with artificial intelligence for the diagnosis of tibial plateau fractures.

作者信息

Xie Yi, Chen Xiaoliang, Yang Huiwen, Wang Honglin, Zhou Hong, Lu Lin, Zhang Jiayao, Liu Pengran, Ye Zhewei

机构信息

Department of Orthopedics Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Laboratory of Intelligent Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Eur J Trauma Emerg Surg. 2025 Feb 21;51(1):119. doi: 10.1007/s00068-025-02793-y.

Abstract

PURPOSE

The application of artificial intelligence (AI) in healthcare has seen widespread implementation, with numerous studies highlighting the development of robust algorithms. However, limited attention has been given to the secure utilization of raw data for medical model training, and its subsequent impact on clinical decision-making and real-world applications. This study aims to assess the feasibility and effectiveness of an advanced diagnostic model that integrates blockchain technology and AI for the identification of tibial plateau fractures (TPFs) in emergency settings.

METHOD

In this study, blockchain technology was utilized to construct a distributed database for trauma orthopedics, images collected from three independent hospitals for model training, testing, and internal validation. Then, a distributed network combining blockchain and deep learning was developed for the detection of TPFs, with model parameters aggregated across multiple nodes to enhance accuracy. The model's performance was comprehensively evaluated using metrics including accuracy, sensitivity, specificity, F1 score, and the area under the receiver operating characteristic curve (AUC). In addition, the performance of the centralized model, the distributed AI model, clinical orthopedic attending physicians, and AI-assisted attending physicians was tested on an external validation dataset.

RESULTS

In the testing set, the accuracy of our distributed model was 0.9603 [95% CI (0.9598, 0.9605)] and the AUC was 0.9911 [95% CI (0.9893, 0.9915)] for TPF detection. In the external validation set, the accuracy reached 0.9636 [95% CI (0.9388, 0.9762)], was slightly higher than that of the centralized YOLOv8n model at 0.9632 [95% CI (0.9387, 0.9755)] (p > 0.05), and exceeded the orthopedic physician at 0.9291 [95% CI (0.9002, 0.9482)] and radiology attending physician at 0.9175 [95% CI (0.8891, 0.9393)], with a statistically significant difference (p < 0.05). Additionally, the centralized model (4.99 ± 0.01 min) had shorter diagnosis times compared to the orthopedic attending physician (25.45 ± 1.92 min) and the radiology attending physician (26.21 ± 1.20 min), with a statistically significant difference (p < 0.05).

CONCLUSION

The model based on the integration of blockchain technology and AI can realize safe, collaborative, and convenient assisted diagnosis of TPF. Through the aggregation of training parameters by decentralized algorithms, it can achieve model construction without data leaving the hospital and may exert clinical application value in the emergency settings.

摘要

目的

人工智能(AI)在医疗保健领域的应用已得到广泛实施,众多研究强调了强大算法的开发。然而,对于用于医学模型训练的原始数据的安全利用及其对临床决策和实际应用的后续影响,关注较少。本研究旨在评估一种先进的诊断模型的可行性和有效性,该模型将区块链技术与AI集成,用于在急诊环境中识别胫骨平台骨折(TPF)。

方法

在本研究中,利用区块链技术构建了一个创伤骨科分布式数据库,从三家独立医院收集图像用于模型训练、测试和内部验证。然后,开发了一个结合区块链和深度学习的分布式网络用于TPF检测,跨多个节点聚合模型参数以提高准确性。使用包括准确率、灵敏度、特异性、F1分数和受试者操作特征曲线下面积(AUC)等指标对模型性能进行全面评估。此外,在外部验证数据集上测试了集中式模型、分布式AI模型、临床骨科主治医师和AI辅助主治医师的性能。

结果

在测试集中,我们的分布式模型用于TPF检测的准确率为0.9603 [95%置信区间(0.9598,0.9605)],AUC为0.9911 [95%置信区间(0.9893,0.9915)]。在外部验证集中,准确率达到0.9636 [95%置信区间(0.9388,0.9762)],略高于集中式YOLOv8n模型的0.9632 [95%置信区间(0.9387,0.9755)](p>0.05),并超过了骨科医师的0.9291 [95%置信区间(0.9002,0.9482)]和放射科主治医师的0.9175 [95%置信区间(0.8891,0.9393)],差异具有统计学意义(p<0.05)。此外,集中式模型(4.99±0.01分钟)的诊断时间比骨科主治医师(25.45±1.92分钟)和放射科主治医师(26.21±1.20分钟)短,差异具有统计学意义(p<0.05)。

结论

基于区块链技术与AI集成的模型可实现TPF的安全、协作和便捷辅助诊断。通过去中心化算法聚合训练参数,可在不使数据离开医院的情况下实现模型构建,并可能在急诊环境中发挥临床应用价值。

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