Sharun Khan, Banu S Amitha
Graduate Institute of Medicine, Yuan Ze University, Taoyuan, 32003, Taiwan.
Amrita Research Centre, Delhi NCR, Amrita Vishwa Vidyapeetham, Faridabad, 121002, Haryana, India.
Vet Res Commun. 2025 Feb 22;49(2):111. doi: 10.1007/s11259-025-10690-3.
Platelet concentrates such as platelet-rich plasma (PRP) are widely used in veterinary regenerative medicine and transfusion therapy. However, the therapeutic efficacy of PRP is highly dependent on its precise characterization, cellular composition, and preparation methods. Without proper standardization, PRP treatments can yield inconsistent results, undermining their clinical utility. A recent study in Veterinary Research Communications underscores the importance of pH measurement as a key quality control parameter for platelet concentrates, including PRP, in veterinary blood banks. Building on these findings and our own recent experience, we propose revised minimum reporting guidelines for the use of PRP in veterinary regenerative medicine. Adherence to minimum reporting guidelines is essential to ensure reproducibility and reduce heterogeneity in PRP therapies. Future research should focus on species-specific protocols and advanced characterization techniques to enhance the therapeutic potential of PRP. By addressing these challenges, PRP can become a cornerstone of regenerative therapies in veterinary medicine, offering safe and effective treatment options for various diseases and disorders.
富含血小板血浆(PRP)等血小板浓缩物在兽医再生医学和输血治疗中广泛应用。然而,PRP的治疗效果高度依赖于其精确的特性、细胞组成和制备方法。如果没有适当的标准化,PRP治疗可能会产生不一致的结果,从而削弱其临床效用。《兽医研究通讯》最近的一项研究强调了pH测量作为兽医血库中血小板浓缩物(包括PRP)关键质量控制参数的重要性。基于这些发现和我们自己最近的经验,我们提出了在兽医再生医学中使用PRP的修订后的最低报告指南。遵守最低报告指南对于确保PRP治疗的可重复性和减少异质性至关重要。未来的研究应侧重于物种特异性方案和先进的表征技术,以提高PRP的治疗潜力。通过应对这些挑战,PRP可以成为兽医再生疗法的基石,为各种疾病和病症提供安全有效的治疗选择。