文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

富血小板血浆疗法发展面临的挑战。

Current Challenges in the Development of Platelet-Rich Plasma-Based Therapies.

机构信息

Microfluidics Cluster UPV/EHU BIOMICs Microfluidics Group Lascaray Research Center University of the Basque Country UPV/EHU 01006, Vitoria-Gasteiz, Spain.

Advance Biological Therapy Unit Hospital Vithas Vitoria 01008, Vitoria-Gasteiz, Spain.

出版信息

Biomed Res Int. 2024 Aug 9;2024:6444120. doi: 10.1155/2024/6444120. eCollection 2024.

DOI:10.1155/2024/6444120
PMID:39157212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11329313/
Abstract

Nowadays, biological therapies are booming and more of these formulations are coming to the market. Platelet-rich plasma, or PRP, is one of the most widely used biological therapies due to its ease of obtention and autologous character. Most of the techniques to obtain PRP are focusing on new processes and methods of optimization. However, not enough consideration is being given to modify the molecular components of PRP to generate more effective formulations with the aim of improving PRP treatments. Therefore, this review covers different novel PRP-obtaining methods that attempt to modify the molecular composition of the plasma.

摘要

如今，生物疗法正在蓬勃发展，越来越多的这类制剂正推向市场。由于易于获取和自体特性，富血小板血浆（PRP）是应用最广泛的生物疗法之一。大多数获取 PRP 的技术都集中在新的工艺和优化方法上。然而，对于修改 PRP 的分子成分以生成更有效的制剂以提高 PRP 治疗效果的关注还不够。因此，本综述涵盖了不同的新型 PRP 获取方法，这些方法试图修改血浆的分子组成。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/07df54cbebf8/BMRI2024-6444120.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/c88c74f03b5e/BMRI2024-6444120.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/df0f9c85501c/BMRI2024-6444120.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/ff42126f553c/BMRI2024-6444120.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/39eff012cbfb/BMRI2024-6444120.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/cface7d458fb/BMRI2024-6444120.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/0dae94709d26/BMRI2024-6444120.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/07df54cbebf8/BMRI2024-6444120.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/c88c74f03b5e/BMRI2024-6444120.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/df0f9c85501c/BMRI2024-6444120.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/ff42126f553c/BMRI2024-6444120.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/39eff012cbfb/BMRI2024-6444120.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/cface7d458fb/BMRI2024-6444120.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/0dae94709d26/BMRI2024-6444120.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/11329313/07df54cbebf8/BMRI2024-6444120.007.jpg

相似文献

[1]
Current Challenges in the Development of Platelet-Rich Plasma-Based Therapies.

Biomed Res Int. 2024

[2]
Method to obtain a plasma rich in platelet- and plasma-growth factors based on water evaporation.

PLoS One. 2024

[3]
[Orthobiologic treatment with platelet-rich plasma: is there sufficient evidence for its recommendation?].

Invest Clin. 2016-3

[4]
Platelet-rich plasma preparation for regenerative medicine: optimization and quantification of cytokines and growth factors.

Stem Cell Res Ther. 2013-6-7

[5]
Profound Properties of Protein-Rich, Platelet-Rich Plasma Matrices as Novel, Multi-Purpose Biological Platforms in Tissue Repair, Regeneration, and Wound Healing.

Int J Mol Sci. 2024-7-19

[6]
Cellular Components and Growth Factor Content of Platelet-Rich Plasma With a Customizable Commercial System.

Am J Sports Med. 2019-3-8

[7]
Addressing Reproducibility in Stem Cell and PRP Therapies.

Trends Biotechnol. 2018-12-19

[8]
Characterization of the molecular composition and in vitro regenerative capacity of platelet-based bioproducts and related subfractions.

Acta Biomater. 2024-3-15

[9]
Review of Dohan Eherenfest et al. (2009) on "Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)".

J ISAKOS. 2024-4

[10]
Exercise-Mobilized Platelet-Rich Plasma: Short-Term Exercise Increases Stem Cell and Platelet Concentrations in Platelet-Rich Plasma.

Arthroscopy. 2019-1

引用本文的文献

[1]
Intra-articular Injections of Allogeneic Platelet-Rich Plasma from Responder Patients for the Treatment of Knee Osteoarthritis: A Pilot and Feasibility Clinical Trial.

Cartilage. 2025-7-29

[2]
Double-Puncture Arthrocentesis in Arthrogenous TMJ Disorders: Bioviscosupplementation vs. Viscosupplementation a Randomized Controlled Trial.

J Clin Med. 2025-5-27

[3]
Minimum reporting guidelines for platelet-rich plasma in veterinary regenerative medicine.

Vet Res Commun. 2025-2-22

[4]
Increasing the concentration of plasma molecules improves the biological activity of platelet-rich plasma for tissue regeneration.

Sci Rep. 2025-2-6

[5]
The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series.

Medicina (Kaunas). 2025-1-7

本文引用的文献

[1]
Method to obtain a plasma rich in platelet- and plasma-growth factors based on water evaporation.

PLoS One. 2024

[2]
Women show a positive response to platelet-rich plasma despite presenting more painful knee osteoarthritis than men.

Knee Surg Sports Traumatol Arthrosc. 2024-10

[3]
Method Based on Ultrafiltration to Obtain a Plasma Rich in Platelet and Plasma Growth Factors.

J Clin Med. 2023-9-13

[4]
New Formulation of Platelet-Rich Plasma Enriched in Platelet and Extraplatelet Biomolecules Using Hydrogels.

Int J Mol Sci. 2023-9-7

[5]
Action of Platelet-Rich Plasma on In Vitro Cellular Bioactivity: More than Platelets.

Int J Mol Sci. 2023-3-10

[6]
Evolution and Clinical Advances of Platelet-Rich Fibrin in Musculoskeletal Regeneration.

Bioengineering (Basel). 2023-1-3

[7]
Modifying Orthobiological PRP Therapies Are Imperative for the Advancement of Treatment Outcomes in Musculoskeletal Pathologies.

Biomedicines. 2022-11-15

[8]
Real-world evidence to assess the effectiveness of platelet-rich plasma in the treatment of knee degenerative pathology: a prospective observational study.

Ther Adv Musculoskelet Dis. 2022-6-14

[9]
Isolation of Platelet-Derived Exosomes from Human Platelet-Rich Plasma: Biochemical and Morphological Characterization.

Int J Mol Sci. 2022-3-5

[10]
Applications and developments of gene therapy drug delivery systems for genetic diseases.

Asian J Pharm Sci. 2021-11

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索