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血库质量控制:血小板浓缩物中 pH 值的评估方法。

Blood bank quality control: pH assessment methods in platelet concentrates.

机构信息

Department of Veterinary Clinical Pathology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Department of Anatomy, Pathology and Veterinary Clinics, Universidade Federal da Bahia, Salvador, Brazil.

出版信息

Vet Res Commun. 2024 Dec;48(6):4129-4132. doi: 10.1007/s11259-024-10536-4. Epub 2024 Sep 14.

Abstract

Platelet concentrates undergo progressive changes during storage, such as a decrease in pH. Additionally, pH and lactate production showed the strongest correlation with platelet survival in posttransfusion viability studies. pH measurement is a straightforward method for evaluating the quality control of blood components in blood bank practice. Our aim was to compare three pH assessment methods for canine platelet concentrates. The pH values of the canine platelet concentrates were assessed on the first day of storage using a calibrated pH meter, a portable gas analyzer and pH-indicator strips. The results from the pH meter and portable gas analyzer measurements were similar. The pH indicator strips presented higher average values compared to the other more reliable methods evaluated, which could result in the use of inadequate blood components. In conclusion, it is recommended to implement pH measurements using a pH meter for quality control in veterinary blood banks.

摘要

血小板浓缩物在储存过程中会发生渐进性变化,例如 pH 值降低。此外,在输血后生存能力研究中,pH 值和乳酸生成与血小板存活的相关性最强。pH 值测量是评估血库实践中血液成分质量控制的一种简单方法。我们的目的是比较三种犬血小板浓缩物的 pH 值评估方法。在储存的第一天,使用校准的 pH 计、便携式气体分析仪和 pH 指示剂条评估犬血小板浓缩物的 pH 值。pH 计和便携式气体分析仪测量结果相似。pH 指示剂条的平均值与评估的其他更可靠方法相比更高,这可能导致使用不适当的血液成分。总之,建议在兽医血库中实施 pH 值测量,以使用 pH 计进行质量控制。

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