Hartley J P, Nogrady S G, Seaton A
Br J Dis Chest. 1979 Jul;73(3):271-6.
Salbutamol dry powder was compared with salbutamol aerosol in 38 asthmatic patients. The study was double-blind and took place over six months. Salbutamol powder in a dose of 200 micrograms per capsule was able to control asthma as well as the aerosol, but some patients needed to increase the frequency of dosage when using the powder. The device used for powder administration, the Rotahaler, was well accepted and was preferred to the pressurized aerosol by one-third of patients. Dry powder administered by Rotahaler allows salbutamol to be given by inhalation to many patients previously using aerosols inefficiently.
对38名哮喘患者的沙丁胺醇干粉和气雾剂进行了比较。该研究为双盲试验，为期6个月。每粒胶囊含200微克剂量的沙丁胺醇干粉与气雾剂控制哮喘的效果相当，但有些患者在使用干粉时需要增加用药频率。用于干粉给药的装置——旋转式吸入器，很受患者欢迎，三分之一的患者更喜欢它而不是压力定量气雾剂。通过旋转式吸入器给予的干粉，能让许多以前低效使用气雾剂的患者通过吸入方式使用沙丁胺醇。
