Chu N S
J Neurol Neurosurg Psychiatry. 1985 Apr;48(4):348-53. doi: 10.1136/jnnp.48.4.348.
A previous study has shown a high incidence of abnormal auditory brainstem responses in alcoholics, particularly when cerebral and/or cerebellar atrophy was present in CT scans. To correlate the electrophysiological findings with definable morphological alterations, quantitative measurements of the brainstem structures in CT scans were made. To determine the relative size of the brainstem, the ratio between the sizes of the brainstem and its cisterns was obtained at the midbrain, upper and lower pons. When compared to the aged-matched control group, the alcoholics as a whole and the alcoholics with abnormal auditory brainstem responses had a decrease in the ratio at all three brainstem levels, but these ratios were not decreased in the alcoholics with the normal auditory brainstem responses. The present data indicate that abnormal brainstem responses in the alcoholics correlated with an increased size of the brainstem cisterns and possible brainstem atrophy.
先前的一项研究表明，酗酒者中听觉脑干反应异常的发生率很高，尤其是在CT扫描显示存在大脑和/或小脑萎缩时。为了将电生理结果与明确的形态学改变相关联，对CT扫描中的脑干结构进行了定量测量。为了确定脑干的相对大小，在中脑、脑桥上段和下段获取了脑干及其脑池大小的比值。与年龄匹配的对照组相比，酗酒者总体以及听觉脑干反应异常的酗酒者在所有三个脑干水平的比值均降低，但听觉脑干反应正常的酗酒者的这些比值并未降低。目前的数据表明，酗酒者的脑干反应异常与脑干脑池增大和可能的脑干萎缩有关。
