Suppr超能文献

韩国残疾人士中按年龄分层的重症新冠风险:考虑残疾类型的全国性研究

Age-Stratified Risk of Severe COVID-19 for People With Disabilities in Korea: Nationwide Study Considering Disability Type.

作者信息

Ryu Boyeong, Jang Hoyeon, Kim Jaiyong, Cho Sung-Il, Kim Seong-Sun

机构信息

Department of Data Science, Korea Disease Control and Prevention Agency (KDCA), Cheongju, Korea.

Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, Korea.

出版信息

J Korean Med Sci. 2025 Feb 24;40(7):e37. doi: 10.3346/jkms.2025.40.e37.

Abstract

BACKGROUND

Understanding disparities in severe coronavirus disease 2019 (COVID-19) outcomes between people with disabilities (PwD) and people without disabilities (PwoD) is crucial, particularly when considering the heterogeneity within PwD and age differences. This study aimed to compare severe COVID-19 outcomes including deaths between PwD and PwoD with analyses stratified by age group and further examined by disability type.

METHODS

This retrospective, population-based cohort study used linked data from national COVID-19 cases and health insurance for individuals aged ≥ 19 years with COVID-19 from January 2020 to October 2022 in the Republic of Korea. Severe outcomes included severe cases and deaths, with logistic regression analysis of the risk disparities between PwD and PwoD based on age group and disability types. The subgroup analysis considered epidemic periods, accounting for the severe acute respiratory syndrome coronavirus 2 variant circulation.

RESULTS

The risk of severe COVID-19 outcomes and deaths among PwD varied by age and disability type. While severe outcomes were most prevalent in the older age groups for both PwD and PwoD, younger PwD faced a markedly higher risk-up to eightfold-compared to PwoD. The risk of disability status was greater than that of comorbidities in the 19-39 age group. Among disability types, individuals with internal organs-related and intellectual disabilities showed higher risk disparities with PwoD in severe outcomes than other types of disabilities. Throughout the pandemic, the disparity in death risk remained similar, with a slight increase in disparity during the omicron period for all severe outcomes in the age groups 19-39 and 40-64 years.

CONCLUSION

Prioritizing younger PwD, along with older age groups and people with comorbidities, is crucial in addressing public health crises. Risk-based prioritization is important to reduce overall risk. This includes prioritizing people with nternal organs-related and intellectural disabilities, who face higher health risks among PwD during a pandemic when resources are limited and time is of the essence.

摘要

背景

了解2019年冠状病毒病(COVID-19)严重后果在残疾人群体(PwD)和非残疾人群体(PwoD)之间的差异至关重要,尤其是考虑到PwD内部的异质性和年龄差异时。本研究旨在比较PwD和PwoD之间包括死亡在内的严重COVID-19后果,并按年龄组进行分层分析,进一步按残疾类型进行考察。

方法

这项基于人群的回顾性队列研究使用了2020年1月至2022年10月韩国≥19岁COVID-19患者的全国COVID-19病例和健康保险的关联数据。严重后果包括重症病例和死亡,基于年龄组和残疾类型对PwD和PwoD之间的风险差异进行逻辑回归分析。亚组分析考虑了流行时期,同时考虑了严重急性呼吸综合征冠状病毒2变异株的传播情况。

结果

PwD中严重COVID-19后果和死亡的风险因年龄和残疾类型而异。虽然PwD和PwoD中严重后果在老年人群体中最为普遍,但年轻的PwD面临的风险明显更高——与PwoD相比高达八倍。在19 - 39岁年龄组中,残疾状态的风险大于合并症的风险。在残疾类型中,与内脏器官相关和智力残疾的个体在严重后果方面与PwoD的风险差异高于其他类型的残疾。在整个疫情期间,死亡风险差异保持相似,在奥密克戎时期年龄组19 - 39岁和40 - 64岁的所有严重后果中差异略有增加。

结论

在应对公共卫生危机时,优先考虑年轻的PwD以及老年人群体和合并症患者至关重要。基于风险的优先排序对于降低总体风险很重要。这包括优先考虑与内脏器官相关和智力残疾的人群,在资源有限且时间紧迫的大流行期间,他们在PwD中面临更高的健康风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/db26/11858602/01ee6dfe2aab/jkms-40-e37-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验