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具有可变二次流的聚丙烯蜂窝状膜肺的氧气和二氧化碳传输

Oxygen and CO2 transfer of a polypropylene dimpled membrane lung with variable secondary flows.

作者信息

Dorrington K L, Ralph M E, Bellhouse B J, Gardaz J P, Sykes M K

出版信息

J Biomed Eng. 1985 Apr;7(2):89-99. doi: 10.1016/0141-5425(85)90036-6.

DOI:10.1016/0141-5425(85)90036-6
PMID:3999727
Abstract

Gas transfer performance is presented for one form of the Oxford membrane lung in which vortex mixing is induced in blood flow across a dimpled polypropylene membrane. Dimensional analysis has been used to define the parameters characterizing mass transfer in the device, and of three fluid mechanical parameters: Reynolds number based on peak pulsation velocity, Strouhal number, and ratio of mean to oscillatory flows, only the first has been found to affect mass transfer significantly in the ranges studied. For oxygenation, rated flows in excess of 5 l min-1 m-2 are measured. A new definition is presented for a rated flow for extracorporeal CO2 removal and values in excess of 1.2 l min-1 m-2 are obtained.

摘要

本文介绍了一种牛津膜肺的气体传输性能,该膜肺通过在有凹坑的聚丙烯膜表面形成的血流中诱导涡流混合来实现气体传输。采用量纲分析来定义该装置中表征传质的参数,在所研究的范围内,三个流体力学参数(基于峰值脉动速度的雷诺数、斯特劳哈尔数以及平均流与振荡流的比值)中,只有第一个参数对传质有显著影响。对于氧合,测得的额定流量超过5 l min-1 m-2。本文给出了体外二氧化碳清除额定流量的新定义,并得到了超过1.2 l min-1 m-2的值。

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A randomized comparison of total extracorporeal CO2 removal with conventional mechanical ventilation in experimental hyaline membrane disease.实验性透明膜病中体外二氧化碳完全清除与传统机械通气的随机对照研究
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