The Antimicrobial Resistance of : A 5-Year Retrospective Analysis at a Tertiary Hospital in Jordan.

infections are a global health concern, increasingly complicated by rising antimicrobial resistance (AMR). This study analyzed the prevalence and AMR patterns of circulating species in Amman, Jordan, using electronic records from a tertiary teaching hospital's microbiology lab (from 2017 to 2022). Complete records of isolates (n = 2673) were assessed by sample type, species, and AMR. Among positive blood samples, accounted for the majority (38.7%), followed by (19.0%), (18.3%), (14.6%), and (9.5%). Non- species demonstrated higher resistance to Caspofungin, notably (23.1%), (30.0%), and (32.0%), compared to (1.9%). In high vaginal swabs, was most prevalent (63.7%), with also notable (28.6%); Fluconazole resistance in remained low (2.0%). Across all pooled isolates, AMR was similar between inpatients and outpatients, except for Micafungin, where inpatient resistance was significantly higher. In conclusion, non- species predominated in blood infections and demonstrated pronounced AMR. Micafungin resistance was notably higher among inpatients. Variations in species and AMR by sample type suggest that aggregating samples in registry studies may obscure critical patterns.