Rodriguez-Lopez Victor, Dorronsoro Carlos, de Castro Alberto
Institute of Optics, Spanish National Research Council (IO-CSIC), Madrid, Spain.
Optom Vis Sci. 2025 Apr 1;102(4):196-203. doi: 10.1097/OPX.0000000000002239. Epub 2025 Feb 25.
Direct subjective refraction (DSR) is a novel method for refractive error measurements that uses temporal changes in defocus and a flicker minimization task. The computational models developed here are a framework for improving this clinical method.
This study aimed to model the measurement of refractive error with the DSR method, which uses rapid changes in optical power and a bichromatic (red/blue) stimulus.
The polychromatic point spread function of the eye was used to simulate the retinal image projected in DSR method, and an image quality (IQ) metric was defined based on the spatial frequencies of the retinal image. Three tasks were modeled: blur minimization (BM), monochromatic flicker minimization (MFM), and polychromatic flicker minimization or DSR. A metric was defined for each task and studied through focus in a ±3-D range. Whereas BM was modeled using only the IQ of the projected images, MFM and DSR metrics were a function of the IQ of the average retinal image and a metric to quantify the similarity (flicker) in the image. The width of the through-focus peak was used to compare between tasks, and different values of pupil size and spherical aberration were studied.
The through-focus 90% peak width was 0.48, 0.16, and 0.19 D for BM, MFM, and DSR tasks, respectively, which agreed well with previous experimental data. The 90% peak width increased for small pupils and with increasing values of spherical aberration in BM and MFM, but it remained relatively constant in DSR model.
The developed models explained previous experimental findings that reported a higher repeatability of the DSR compared with the traditional refraction method.
直接主观验光(DSR)是一种用于测量屈光不正的新方法,它利用散焦的时间变化和闪烁最小化任务。这里开发的计算模型是改进这种临床方法的一个框架。
本研究旨在用DSR方法对屈光不正测量进行建模,该方法使用光焦度的快速变化和双色(红/蓝)刺激。
用眼睛的多色点扩散函数来模拟DSR方法中投射的视网膜图像,并基于视网膜图像的空间频率定义了一个图像质量(IQ)指标。对三个任务进行了建模:模糊最小化(BM)、单色闪烁最小化(MFM)和多色闪烁最小化或DSR。为每个任务定义了一个指标,并在±3D范围内通过聚焦进行研究。BM仅使用投射图像的IQ进行建模,而MFM和DSR指标是平均视网膜图像IQ的函数以及用于量化图像中相似性(闪烁)的指标。通过聚焦峰值的宽度用于比较不同任务,并研究了瞳孔大小和球差的不同值。
BM、MFM和DSR任务的聚焦90%峰值宽度分别为0.48D、0.16D和0.19D,与先前的实验数据吻合良好。在BM和MFM中,小瞳孔和球差增加时,90%峰值宽度增大,但在DSR模型中保持相对恒定。
所开发的模型解释了先前的实验结果,即与传统验光方法相比,DSR具有更高的可重复性。