From the Instituto de Óptica, Consejo Superior de Investigaciones Científicas, Madrid, Spain (Lago, de Castro, Marcos); 2Eyes Vision SL, Madrid, Spain (Lago); Center for Visual Sciences, The Institute of Optics and Flaum Eye Institute, University of Rochester, Rochester, New York (Marcos).
J Cataract Refract Surg. 2023 Nov 1;49(11):1153-1159. doi: 10.1097/j.jcrs.0000000000001260.
To evaluate computationally the optical performance of AcrySof IQ Vivity extended depth-of-focus (EDOF) intraocular lenses (IOLs) in post-laser in situ keratomileusis (LASIK) eyes.
Visual Optics and Biophotonics Laboratory, Madrid, Spain.
Experimental study.
Computer pseudophakic eye models were implemented using reported post-LASIK corneal aberrations (refractive corrections from -7.5 to +4.5 diopters [D]) and virtually implanted with monofocal (AcrySof IQ) or EDOF (AcrySof IQ Vivity) IOLs. Retinal image quality was quantified through visual Strehl (VS). The depth of focus (DOF) was calculated from the through-focus VS curves. Halos were estimated from the light spread in the image of a pinhole. Those quantitative parameters were obtained for 5.0 and 3.0 mm pupil diameters.
Simulated virgin eyes showed VS of 0.89/0.99 with monofocal IOLs and 0.74/0.52 with EDOF IOLs for 5.0/3.0 mm pupils at best focus. VS decreased with induced spherical aberration (SA) by 25% and with induced SA + coma by 61% on average (3.0 mm pupils). The DOF was 2.50 D in virgin eyes with EDOF IOLs, 1.66 ± 0.30 and 2.54 ± 0.31 D ( P < .05) on average in post-LASIK eyes for 3.0 mm pupils, monofocal and EDOF IOLs, respectively. Halos were more sensitive to SA induction for 5.0 mm pupils, and induction of positive SA (myopic LASIK) resulted in reduced halos with the EDOF when compared with the monofocal IOLs, by 1.62 (SA) and 1.86 arc min (SA + coma), on average.
Computer post-LASIK pseudophakic eye models showed that the DOF was less dependent on the presence of SA and coma with EDOF IOLs and that halos were reduced with EDOF IOLs compared with the monofocal IOL for a range of SA.
通过计算评估 AcrySof IQ Vivity 扩展景深（EDOF）人工晶状体（IOL）在 LASIK 后眼的光学性能。
西班牙马德里视觉光学与生物光子学实验室。
实验研究。
使用报道的 LASIK 后角膜像差（从-7.5 至+4.5 屈光度[D]的屈光矫正），对计算机模拟的假眼模型进行实施，并虚拟植入单焦点（AcrySof IQ）或 EDOF（AcrySof IQ Vivity）IOL。通过视觉条纹（VS）量化视网膜图像质量。通过聚焦 VS 曲线计算景深（DOF）。通过小孔图像中的光扩展估计晕影。对于 5.0 和 3.0 毫米瞳孔直径，获得了这些定量参数。
模拟的正常眼在最佳焦点处，5.0/3.0 毫米瞳孔时，单焦点 IOL 为 0.89/0.99，EDOF IOL 为 0.74/0.52。诱导的球差（SA）减少 25%，诱导的 SA+彗差减少 61%（平均 3.0 毫米瞳孔）时，VS 会降低。EDOF IOL 在正常眼中的景深为 2.50 D，LASIK 后眼 3.0 毫米瞳孔时，单焦点和 EDOF IOL 的平均景深分别为 1.66±0.30 和 2.54±0.31 D（P<.05）。5.0 毫米瞳孔对 SA 诱导更敏感，与单焦点 IOL 相比，EDOF 诱导正 SA（近视 LASIK）时，晕影减少 1.62（SA）和 1.86 弧分（SA+彗差）。
LASIK 后计算机模拟的假眼模型表明，EDOF IOL 的 DOF 对 SA 和彗差的依赖性较小，与单焦点 IOL 相比，在一定范围内的 SA 时，EDOF IOL 的晕影减少。
