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评估下肢创伤重建中二次减积手术的预测因素和结果:一项回顾性队列研究。

Assessing predictors and outcomes of secondary debulking procedures in lower limb trauma reconstruction: A retrospective cohort study.

作者信息

Mastroiacovo Alessandro, Pantelides Alexandros, Hardman Lotte, Wright Thomas, Khan Umraz

机构信息

Southmead Hospital, Southmead Road, Bristol BS10 5NB, UK; Università degli Studi di Milano, Via Festa del Perdono, 7, 20122 Milano, Italy.

Southmead Hospital, Southmead Road, Bristol BS10 5NB, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2025 Apr;103:218-225. doi: 10.1016/j.bjps.2025.01.025. Epub 2025 Feb 6.

DOI:10.1016/j.bjps.2025.01.025
PMID:39999690
Abstract

The goal of flap design in orthoplastic trauma is to provide stable, vascularized coverage for fractures, prevent infection and enable fracture union. This study aimed to improve orthoplastic trauma outcomes by identifying factors that predict the need for secondary flap debulking in severe open lower limb fractures. A retrospective cohort of 893 patients treated at a UK major trauma center was analyzed, with 126 patients (14.1%) requiring secondary debulking post-fracture union. Logistic regression evaluated the impact of sex, age, injury location and flap type on debulking likelihood. Our results showed that men were significantly less likely to request and undergo debulking (OR = 0.33, p < 0.001), whereas younger patients had higher odds (OR = 0.97, p < 0.001). The requests for debulking of flaps around the ankle (OR = 4.93, p < 0.001) and dorsum of the foot (OR = 5.28, p < 0.05) were significantly higher compared to midshaft to distal third of the tibia and plantar foot flaps. Medial plantar local fasciocutaneous and gracilis free flaps had significantly lower debulking rates (p < 0.001). Functional outcomes improved after debulking, with Enneking scores increasing from 28.0 (70.0%) to 33.0 (82.5%) (V = 200.5, p < 0.001). Post-debulking complications affected 16.8% of cases, mostly minor, with no total flap loss. This predictive model highlights how factors such as sex, age, injury zone and flap choice can guide surgical planning to enhance function, aesthetics and quality of life in limb reconstruction.

摘要

整形外科创伤中皮瓣设计的目标是为骨折提供稳定的、有血运的覆盖,预防感染并促进骨折愈合。本研究旨在通过确定预测严重开放性下肢骨折二次皮瓣减容需求的因素来改善整形外科创伤的治疗效果。分析了在英国一家主要创伤中心接受治疗的893例患者的回顾性队列,其中126例患者(14.1%)在骨折愈合后需要二次减容。逻辑回归评估了性别、年龄、损伤部位和皮瓣类型对减容可能性的影响。我们的结果显示,男性要求并接受减容的可能性显著更低(比值比=0.33,p<0.001),而年轻患者的可能性更高(比值比=0.97,p<0.001)。与胫骨中下段至远端三分之一和足底皮瓣相比,踝关节周围(比值比=4.93,p<0.001)和足背(比值比=5.28,p<0.05)皮瓣的减容需求显著更高。内侧足底局部筋膜皮瓣和股薄肌游离皮瓣的减容率显著更低(p<0.001)。减容后功能结果得到改善,Enneking评分从28.0(70.0%)提高到33.0(82.5%)(V=200.5,p<0.001)。减容后并发症影响了16.8%的病例,大多为轻微并发症,无皮瓣完全坏死。这种预测模型突出了性别、年龄、损伤区域和皮瓣选择等因素如何指导手术规划,以提高肢体重建的功能、美观和生活质量。

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