Charmot G, Bricaire F, Bastin R
Nouv Presse Med. 1979 Jan 6;8(1):35-8.
Plasmodium ovale as the causative parasite in attacks of malaria is rare. Nevertheless, the number of cases seen in France would seem to be on the increase. In 137 attacks of malaria collected between 1967 and 1978, Plasmodium ovale was found on 13 occasions. The main characteristics of this form of malaria are, apart from its benign nature, the usual absence of any recurrence and a very variable incubation period, ranging from fifteen days to several months or even a year (with an average of 3.2 months). It is thus important to bear this diagnosis in mind, even if a long period elapsed since return from an endemic area, and it will be realised that adequate chemoprophylaxis using a schizonticide does not offer protection from forms with a long incubation period. Genetic control of the duration of the period of maturation of exo-erythrocytic forms, i.e. the incubation period, is suggested, identical to that recently advanced in the case of Plasmodium vivax. This would account for the variability and possible long duration of incubation periods. A usual monoclonal character of these infections could explain the virtual absence of recurrences.
卵形疟原虫作为疟疾发作的致病寄生虫较为罕见。然而，在法国所见病例的数量似乎在增加。在1967年至1978年间收集的137例疟疾发作病例中，有13例发现了卵形疟原虫。这种疟疾形式的主要特征是，除了其良性性质外，通常没有任何复发情况，潜伏期变化很大，从15天到几个月甚至一年（平均为3.2个月）。因此，即使自从流行地区返回后已经过去了很长时间，也必须牢记这一诊断，并且会认识到使用裂殖体杀灭剂进行充分的化学预防并不能预防潜伏期长的疟疾形式。有人提出对红细胞外期成熟时间即潜伏期进行遗传控制，这与最近在间日疟原虫病例中提出的情况相同。这可以解释潜伏期的变异性和可能的持续时间。这些感染通常具有单克隆特征，可以解释几乎没有复发的情况。
