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法国疟疾的流行病学与预防(作者译)

[Epidemiology and prophylaxis of malaria in France (author's transl)].

作者信息

Bastin R, Charmot G

出版信息

Nouv Presse Med. 1980 Mar 22;9(14):1003-6.

PMID:6988801
Abstract

A study of 100 cases of malaria in France, 98 of which were imported, shows the strong predominance (83%) of Plasmodium falciparum and of contamination in Africa (86%). The reasons why malaria is rare among tourists returning from Asia are given. The risk of re-introduction of the disease into France seems to be slight, especially for P. falciparum. Chemoprophylaxis is easy when aminoquinolines can be recommended, but much more complicated otherwise, the reasons for failure being the lack of effect of other drugs on pre-erythrocytic forms, resistance to chemotherapy and lack of information or carelessness.

摘要

对法国100例疟疾病例的研究表明,其中98例为输入性病例,恶性疟原虫占主导地位(83%),且感染源多为非洲(86%)。文中给出了从亚洲返回的游客中疟疾罕见的原因。该疾病再次传入法国的风险似乎较小,尤其是恶性疟原虫。当可以推荐氨基喹啉时,化学预防很容易,但在其他情况下则要复杂得多,失败的原因包括其他药物对红细胞前期形式无效、对化疗产生耐药性以及缺乏信息或粗心大意。

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